Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXA2R | P21731 | 12/20 | 0.62 |
| ▸ | PTGDR2 | Q9Y5Y4 | 4/20 | 0.49 |
| ▸ | PTGDR | Q13258 | 3/20 | 0.49 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | DRD1 | P21728 | 1/20 | 0.49 |
| ▸ | CCKAR | P32238 | 1/20 | 0.49 |
| ▸ | TBXAS1 | P24557 | 8/20 | 0.46 |
| ▸ | RB1 | P06400 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7778008 | 0.91 | TBXA2R (0.76) | TBXA2RTBXAS1 | |
| SCHEMBL8115716 | 0.90 | TBXA2R (0.53) | TBXA2RPTGDR2PTGDRABCB11CYP2C9 | |
| SCHEMBL9247892 | 0.87 | TBXA2R (0.82) | TBXA2RPTGDR2PTGDRABCB11CYP2C9 | |
| SCHEMBL7778079 | 0.82 | TBXA2R (0.69) | TBXA2RTBXAS1 | |
| SCHEMBL8118452 | 0.81 | TBXA2R (0.65) | TBXA2RTBXAS1 | |
| SCHEMBL15052228 | 0.81 | TBXA2R (0.81) | TBXA2RPTGDR2PTGDRABCB11CYP2C9 | |
| SCHEMBL8120505 | 0.80 | TBXA2R (0.61) | TBXA2RTBXAS1 | |
| SCHEMBL7776165 | 0.80 | TBXA2R (0.56) | TBXA2RPTGDR2PTGDRABCB11CYP2C9 | |
| SCHEMBL12675846 | 0.77 | TBXA2R (0.82) | TBXA2RPTGDR2PTGDRABCB11CYP2C9 | |
| Terutroban SCHEMBL43629 | 0.77 | TBXA2R (1.00) | TBXA2RTBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0864561-B1 | Benzenesulfonylamine derivatives,process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 2001-09-05 | — | — | EP | disclosed |