Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXA2R | P21731 | 12/20 | 0.56 |
| ▸ | TBXAS1 | P24557 | 8/20 | 0.44 |
| ▸ | PTGDR2 | Q9Y5Y4 | 4/20 | 0.44 |
| ▸ | PTGDR | Q13258 | 3/20 | 0.44 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | DRD1 | P21728 | 1/20 | 0.44 |
| ▸ | CCKAR | P32238 | 1/20 | 0.44 |
| ▸ | RB1 | P06400 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8113368 | 0.92 | TBXA2R (0.49) | TBXA2RTBXAS1PTGDR2PTGDRABCB11 | |
| SCHEMBL7771855 | 0.92 | TBXA2R (0.68) | TBXA2RTBXAS1 | |
| SCHEMBL7778084 | 0.85 | TBXA2R (0.54) | TBXA2RTBXAS1PTGDR2PTGDRABCB11 | |
| SCHEMBL7779019 | 0.84 | TBXA2R (0.69) | TBXA2RTBXAS1 | |
| SCHEMBL8113863 | 0.84 | TBXA2R (0.59) | TBXA2RTBXAS1 | |
| SCHEMBL8115014 | 0.84 | TBXA2R (0.57) | TBXA2RTBXAS1 | |
| SCHEMBL7776177 | 0.82 | TBXA2R (0.61) | TBXA2RTBXAS1 | |
| SCHEMBL9247892 | 0.81 | TBXA2R (0.82) | TBXA2RTBXAS1PTGDR2PTGDRABCB11 | |
| SCHEMBL7778006 | 0.80 | TBXA2R (0.66) | TBXA2RTBXAS1 | |
| SCHEMBL7776213 | 0.80 | TBXA2R (0.62) | TBXA2RTBXAS1PTGDR2PTGDRABCB11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0864561-B1 | Benzenesulfonylamine derivatives,process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 2001-09-05 | — | — | EP | disclosed |
| US-6013667-A | Benzenesulfonylamine compounds, process for preparing them and pharmaceutical compositions | ADIR ET COMPAGNIE (FR) | 2000-01-11 | — | — | US | disclosed |
| EP-0864561-A1 | Benzenesulfonylamine derivatives,process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1998-09-16 | — | — | EP | disclosed |