SCHEMBL77763

SCHEMBL77763

OCCc1ccc(O)c(-n2nc3ccccc3n2)c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.58
NPC1 O15118 2/20 0.58
RAB9A P51151 2/20 0.58
KDM4E B2RXH2 5/20 0.54
POLB P06746 4/20 0.54
ALDH1A1 P00352 3/20 0.54
HPGD P15428 3/20 0.54
ALOX15 P16050 2/20 0.54
MAPK1 P28482 1/20 0.54
HSD17B10 Q99714 1/20 0.54
MAPT P10636 2/20 0.49
BACE1 P56817 2/20 0.49
ALOX5 P09917 1/20 0.49
GAA P10253 1/20 0.49
KMT2A Q03164 2/20 0.37
MEN1 O00255 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
IGF1R P08069 1/20 0.37
CA2 P00918 1/20 0.36
GFER P55789 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29517159 1.00 LMNA (0.58) LMNANPC1RAB9AKDM4EPOLB
Hydrogen Sulfide SCHEMBL8439446 0.98 LMNA (0.56) LMNANPC1RAB9AKDM4EPOLB
Ammonia Solution, Strong SCHEMBL8437470 0.98 LMNA (0.56) LMNANPC1RAB9AKDM4EPOLB
SCHEMBL30240898 0.91 LMNA (0.55) LMNANPC1RAB9AKDM4EPOLB
SCHEMBL75064 0.91 LMNA (0.55) LMNANPC1RAB9AKDM4EPOLB
Ether SCHEMBL8434807 0.91 NPC1 (0.52) LMNANPC1RAB9AKDM4EPOLB
SCHEMBL7564171 0.90 LMNA (0.54) LMNANPC1RAB9AKDM4EPOLB
SCHEMBL11376360 0.88 KDM4E (0.51) LMNANPC1RAB9AKDM4EPOLB
SCHEMBL76414 0.87 NPC1 (0.61) LMNANPC1RAB9AKDM4EPOLB
SCHEMBL30240912 0.87 NPC1 (0.61) LMNANPC1RAB9AKDM4EPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 328 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260146144-A1 SYNERGISTIC STABILIZER COMPOSITIONS AND METHODS FOR USING SAME FOR PROTECTING ORGANIC MATERIALS FROM UV LIGHT AND THERMAL DEGRADATION CYTEC INDUSTRIES INC. (US) 2026-05-28 US claimed
EP-4574893-A1 BARIUM MAGNESIUM SILICATES AND 2-HYDROXYPHENYLBENZOTRIAZOLE UV ABSORBERS IN A GREENHOUSE FILM RHODIA OPERATIONS (FR) 2025-06-25 EP claimed
WO-2025099143-A1 COMPOSITIONS FOR STABILIZING POLYMERIC MATERIALS AGAINST UV LIGHT THERMAL AND GAS FADING DEGRADATION CYTEC INDUSTRIES INC. (US) 2025-05-15 WO claimed
WO-2025099141-A1 STABILIZING COMPOSITIONS FOR POLYMERIC MATERIALS CYTEC INDUSTRIES INC. (US) 2025-05-15 WO claimed
WO-2025056330-A1 STABILIZED POLYMER COMPOSITIONS WITH IMPROVED COLOR RESISTANCE CYTEC INDUSTRIES INC. (US) 2025-03-20 WO claimed
US-12215215-B2 Stabilizer compositions and methods for using same for protecting polymeric organic materials from UV light and thermal degradation CYTEC INDUSTRIES INC. (US) 2025-02-04 US claimed
WO-2024134381-A1 COMPOSITIONS FOR OPHTHALMOLOGIC DEVICES JOHNSON & JOHNSON VISION CARE, INC. (US) 2024-06-27 WO claimed
WO-2024134382-A1 COMPOSITIONS FOR OPHTHALMOLOGIC DEVICES JOHNSON & JOHNSON VISION CARE, INC. (US) 2024-06-27 WO claimed
WO-2024134384-A1 COMPOSITIONS FOR OPHTHALMOLOGIC DEVICES JOHNSON & JOHNSON VISION CARE, INC. (US) 2024-06-27 WO claimed
EP-4363506-A1 COMPOSITIONS AND METHODS FOR PROTECTING COATINGS FROM THE DELETERIOUS EFFECTS OF EXPOSURE TO UV-C LIGHT Cytec Industries Inc. (US) 2024-05-08 EP claimed
US-20060052491-A1 Synergistic uv absorber combination CIBA SPECIALTY CHEMICALS CORP. 2006-03-09 US claimed
EP-1549713-A1 SYNERGISTIC UV ABSORBER COMBINATION Ciba SC Holding AG (CH) 2005-07-06 EP claimed
US-20040167249-A1 Phase change inks with isocyanate-derived antioxidants and UV stabilizers XEROX CORPORATION 2004-08-26 US claimed
WO-2004031294-A1 SYNERGISTIC UV ABSORBER COMBINATION CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2004-04-15 WO claimed
EP-1308084-A1 Synergistic UV absorber combination Ciba SC Holding AG (CH) 2003-05-07 EP claimed
US-6432184-B1 POLYDIMETHYLAMMONIUM CHLORIDE WITH COLORFASTNESS XEROX CORPORATION 2002-08-13 US claimed
US-5980851-A Transparent electrically conductive plate NIPPON OIL, CO., LTD. (JP) 1999-11-09 US claimed
US-5770314-A Transparent electrically conductive plate NIPPON OIL CO., LTD. (JP) 1998-06-23 US claimed
EP-0131468-B1 ULTRAVIOLET ABSORBING POLYMERS COMPRISING 2-HYDROXY-5-ACRYLYLOXALKYLPHENYL-2H-BENZOTRIAZOLES IOLAB CORPORATION (US) 1990-01-17 EP claimed
EP-0131468-A2 Ultraviolet absorbing polymers comprising 2-hydroxy-5-acrylyloxalkylphenyl-2H-benzotriazoles IOLAB CORPORATION (US) 1985-01-16 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260146144-A1 SYNERGISTIC STABILIZER COMPOSITIONS AND METHODS FOR USING SAME FOR PROTECTING ORGANIC MATERIALS FROM UV LIGHT AND THERMAL DEGRADATION RAD52, XRCC6, RAD23B LMNA 1626/4885NPC1 3737/4885RAB9A 4242/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.