Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | P2RY2 | P41231 | 3/20 | 0.45 |
| ▸ | P2RY4 | P51582 | 3/20 | 0.45 |
| ▸ | P2RY6 | Q15077 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | PDE3A | Q14432 | 3/20 | 0.39 |
| ▸ | CACNA1F | O60840 | 2/20 | 0.39 |
| ▸ | ALB | P02768 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | CACNA1D | Q01668 | 2/20 | 0.39 |
| ▸ | CACNA1S | Q13698 | 2/20 | 0.39 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.39 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.39 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | MTOR | P42345 | 1/20 | 0.38 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.38 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.38 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.38 |
| ▸ | POLG | P54098 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7638345 | 0.85 | DNMT1 (0.40) | POLBADRB1DNMT1 | |
| SCHEMBL2580883 | 0.82 | POLB (0.59) | POLBP2RY2P2RY4P2RY6LMNA | |
| SCHEMBL1939479 | 0.79 | POLB (0.68) | POLBP2RY2P2RY4P2RY6LMNA | |
| SCHEMBL3200090 | 0.79 | POLB (0.68) | POLBP2RY2P2RY4P2RY6LMNA | |
| SCHEMBL15617962 | 0.79 | POLB (0.68) | POLBP2RY2P2RY4P2RY6LMNA | |
| SCHEMBL5188351 | 0.78 | POLB (0.57) | POLBP2RY2P2RY4P2RY6LMNA | |
| SCHEMBL5186987 | 0.78 | POLB (0.57) | POLBP2RY2P2RY4P2RY6LMNA | |
| SCHEMBL7772982 | 0.77 | POLB (0.63) | POLBP2RY2P2RY4P2RY6LMNA | |
| SCHEMBL5666385 | 0.77 | POLB (0.68) | POLBP2RY2P2RY4P2RY6LMNA | |
| SCHEMBL3424606 | 0.77 | POLB (0.68) | POLBP2RY2P2RY4P2RY6LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0423839-B1 | Polynucleotides and probes useful in solution phase nucleic acid sandwich assay | BAYER AG (US) | 2001-08-16 | — | — | EP | disclosed |
| EP-0225807-B1 | Solution phase nucleic acid sandwich assay and polynucleotide probes useful therein | CHIRON CORP (US) | 1994-10-19 | — | — | EP | disclosed |
| US-5093232-A | Detection of dna sequences | CHIRON CORPORATION (US) | 1992-03-03 | — | — | US | disclosed |
| US-4910300-A | Adding additional nucleotide to modified nucleotide at | CHIRON CORPORATION (US) | 1990-03-20 | — | — | US | disclosed |
| EP-0225807-A2 | Solution phase nucleic acid sandwich assay and polynucleotide probes useful therein | CHIRON CORPORATION (US) | 1987-06-16 | — | — | EP | disclosed |