⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7776564 | 0.92 | — | — | |
| SCHEMBL7776418 | 0.91 | BRD4 (0.45) | — | |
| SCHEMBL7770192 | 0.90 | BRD4 (0.39) | — | |
| SCHEMBL7774766 | 0.90 | — | — | |
| SCHEMBL7774884 | 0.89 | POLB (0.47) | — | |
| SCHEMBL6705396 | 0.88 | L3MBTL1 (0.51) | — | |
| SCHEMBL7774890 | 0.88 | — | — | |
| SCHEMBL7770171 | 0.87 | BRD4 (0.44) | — | |
| SCHEMBL7774780 | 0.87 | MEN1 (0.44) | — | |
| SCHEMBL7774882 | 0.85 | BRD4 (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1125936-A2 | Aryl substituted azabenzimidazoles and their use in the treatment of HIV and AIDS related diseases | Pfizer Products Inc. (US) | 2001-08-22 | — | — | EP | claimed |
| US-6242461-B1 | Use of aryl substituted azabenzimidazoles in the treatment of HIV and AIDS related diseases | PFIZER INC. | 2001-06-05 | — | — | US | claimed |
| EP-1125936-A2 | Aryl substituted azabenzimidazoles and their use in the treatment of HIV and AIDS related diseases | Pfizer Products Inc. (US) | 2001-08-22 | — | — | EP | disclosed |
| US-6242461-B1 | Use of aryl substituted azabenzimidazoles in the treatment of HIV and AIDS related diseases | PFIZER INC. | 2001-06-05 | — | — | US | disclosed |