Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DUT | P33316 | 8/20 | 0.45 |
| ▸ | TYMP | P19971 | 2/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.36 |
| ▸ | TYMS | P04818 | 1/20 | 0.35 |
| ▸ | TOP2A | P11388 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | RNASE1 | P07998 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27125397 | 1.00 | DUT (0.45) | DUTTYMPTHRBP2RY14TYMS | |
| SCHEMBL6312752 | 1.00 | DUT (0.45) | DUTTYMPTHRBP2RY14TYMS | |
| SCHEMBL3574271 | 0.94 | DUT (0.49) | DUTTYMPTOP2AMEN1KMT2A | |
| SCHEMBL4731659 | 0.87 | TOP2A (0.49) | TYMPTYMSTOP2ARNASE1 | |
| SCHEMBL5693267 | 0.87 | TOP2A (0.49) | TYMPTYMSTOP2ARNASE1 | |
| SCHEMBL25399262 | 0.87 | DUT (0.46) | DUTTYMPP2RY14TYMSTOP2A | |
| SCHEMBL25400207 | 0.87 | HSP90AA1 (0.47) | TYMPTYMSTOP2AHSP90AA1RNASE1 | |
| SCHEMBL14062471 | 0.85 | DUT (0.47) | DUTTYMPP2RY14TYMSMEN1 | |
| SCHEMBL19841219 | 0.85 | DUT (0.60) | DUTTYMPP2RY14TYMS | |
| SCHEMBL14403996 | 0.85 | DUT (0.60) | DUTTYMPP2RY14TYMS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0423839-B1 | Polynucleotides and probes useful in solution phase nucleic acid sandwich assay | BAYER AG (US) | 2001-08-16 | — | — | EP | disclosed |
| EP-0225807-B1 | Solution phase nucleic acid sandwich assay and polynucleotide probes useful therein | CHIRON CORP (US) | 1994-10-19 | — | — | EP | disclosed |
| US-5093232-A | Detection of dna sequences | CHIRON CORPORATION (US) | 1992-03-03 | — | — | US | disclosed |
| US-4910300-A | Adding additional nucleotide to modified nucleotide at | CHIRON CORPORATION (US) | 1990-03-20 | — | — | US | disclosed |