SCHEMBL7777157

SCHEMBL7777157

CCOC(=O)C(CCCCC(C)C)(CC(C)C)C(=O)OCC

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MMP8 P22894 1/20 0.46
MEN1 O00255 3/20 0.42
KMT2A Q03164 3/20 0.42
CYP4F2 P78329 3/20 0.41
CYP4A11 Q02928 3/20 0.41
PKM P14618 2/20 0.41
THRB P10828 1/20 0.41
HTT P42858 2/20 0.40
L3MBTL1 Q9Y468 2/20 0.37
MAPT P10636 1/20 0.37
ATM Q13315 1/20 0.37
HPGD P15428 1/20 0.34
ALDH1A1 P00352 2/20 0.33
LMNA P02545 1/20 0.33
CYP1A2 P05177 1/20 0.33
CYP2C9 P11712 1/20 0.33
CYP2C19 P33261 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
KDM4C Q9H3R0 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7783923 0.96 MMP8 (0.49) MMP8MEN1KMT2ACYP4F2CYP4A11
SCHEMBL7785274 0.93 MEN1 (0.49) MMP8MEN1KMT2ACYP4F2CYP4A11
SCHEMBL7781937 0.93 MEN1 (0.49) MMP8MEN1KMT2ACYP4F2CYP4A11
SCHEMBL7777122 0.90 MEN1 (0.46) MMP8MEN1KMT2ACYP4F2CYP4A11
SCHEMBL7785271 0.89 MEN1 (0.52) MMP8MEN1KMT2ACYP4F2CYP4A11
SCHEMBL4412547 0.88 MMP8 (0.47) MMP8MEN1KMT2ACYP4F2CYP4A11
SCHEMBL7781952 0.87 MMP8 (0.50) MMP8MEN1KMT2ACYP4F2CYP4A11
SCHEMBL7781947 0.86 MEN1 (0.49) MMP8MEN1KMT2ACYP4F2CYP4A11
SCHEMBL28137704 0.84 MMP8 (0.50) MMP8MEN1KMT2ACYP4F2CYP4A11
SCHEMBL234014 0.83 MMP8 (0.56) MMP8MEN1KMT2ACYP4F2CYP4A11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1141044-A1 SOLID CATALYST COMPONENT FOR OLEFIN POLYMERIZATION, CATALYST FOR OLEFIN POLYMERIZATION AND PROCESS FOR PRODUCING OLEFIN POLYMER Basell Technology Company B.V. (NL) 2001-10-10 EP disclosed
WO-2001036496-A1 SOLID CATALYST COMPONENT FOR OLEFIN POLYMERIZATION, CATALYST FOR OLEFIN POLYMERIZATION AND PROCESS FOR PRODUCING OLEFIN POLYMER BASELL TECHNOLOGY COMPANY B.V. (NL) 2001-05-25 WO disclosed