SCHEMBL7777291

SCHEMBL7777291

CSc1sc2ccsc2c(=O)c1Br

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
GPR35 Q9HC97 1/20 0.33
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7830917 0.80 GPR35 (0.33) GPR35ALDH1A1
SCHEMBL7837355 0.76 GPR35 (0.33) GPR35
SCHEMBL7777235 0.76 GPR35 (0.35) GPR35ALDH1A1
SCHEMBL7834237 0.74
SCHEMBL7775858 0.74 GPR35 (0.40) GPR35
SCHEMBL7834183 0.72 GPR35 (0.39) GPR35
SCHEMBL7775939 0.71 GPR35 (0.32) GPR35
SCHEMBL7834234 0.70
SCHEMBL9016696 0.66 GPR35 (0.38) GPR35
SCHEMBL7769640 0.66 GPR35 (0.35) GPR35ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6294527-B1 ANTIBIOTICS FOR METHACILLIN RESISTANT BACTERIA ZENYAKU KOGYO KABUSHIKI KAISHA (JP) 2001-09-25 US disclosed
EP-0949262-B1 CEPHEM COMPOUNDS ZENYAKU KOGYO KK (JP) 2001-08-22 EP disclosed
EP-1090920-A1 CEPHEM COMPOUNDS ZENYAKU KOGYO KABUSHIKI KAISHA (JP) 2001-04-11 EP disclosed
EP-0949262-A1 CEPHEM COMPOUNDS ZENYAKU KOGYO KABUSHIKIKAISHA (JP) 1999-10-13 EP disclosed