Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ECE1 | P42892 | 2/20 | 0.41 |
| ▸ | ITGB2 | P05107 | 2/20 | 0.39 |
| ▸ | ICAM1 | P05362 | 2/20 | 0.39 |
| ▸ | ITGAL | P20701 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 4/20 | 0.37 |
| ▸ | CA1 | P00915 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6234365 | 0.83 | SMN1; SMN2 (0.42) | CA2 | |
| SCHEMBL6234376 | 0.83 | SMN1; SMN2 (0.42) | CA2 | |
| SCHEMBL1986931 | 0.83 | ECE1 (0.43) | ECE1ITGB2ICAM1ITGALCA2 | |
| SCHEMBL1986933 | 0.83 | ECE1 (0.43) | ECE1ITGB2ICAM1ITGALCA2 | |
| SCHEMBL14199861 | 0.82 | ECE1 (0.47) | ECE1ITGB2ICAM1ITGALCA2 | |
| SCHEMBL9924205 | 0.81 | ECE1 (0.41) | ECE1ITGB2ICAM1ITGALCA2 | |
| SCHEMBL1096294 | 0.78 | ECE1 (0.43) | ECE1ITGB2ICAM1ITGALCA2 | |
| SCHEMBL15095888 | 0.77 | ITGB2 (0.44) | ECE1ITGB2ICAM1ITGALCA2 | |
| SCHEMBL88481 | 0.77 | ECE1 (0.46) | ECE1ITGB2ICAM1ITGALCA2 | |
| SCHEMBL30406637 | 0.77 | ECE1 (0.46) | ECE1ITGB2ICAM1ITGALCA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1127153-A1 | METHOD OF PRODUCING ASPARTIC ACID DERIVATIVES | Bayer Aktiengesellschaft (DE) | 2001-08-29 | — | — | EP | disclosed |
| WO-2000026398-A1 | METHOD OF PRODUCING ASPARTIC ACID DERIVATIVES | BAYER AKTIENGESELLSCHAFT (DE) | 2000-05-11 | — | — | WO | disclosed |