SCHEMBL1986933

SCHEMBL1986933

NC(=O)C[C@H](NCO)C(=O)O

nearest known ligand 0.43

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ECE1 P42892 2/20 0.43
TGFBR1 P36897 1/20 0.42
ITGB2 P05107 2/20 0.41
ICAM1 P05362 2/20 0.41
ITGAL P20701 2/20 0.41
CA2 P00918 3/20 0.39
CA1 P00915 2/20 0.39
ALDH1A1 P00352 1/20 0.39
RAB9A P51151 1/20 0.39
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38
PDCD1LG2 Q9BQ51 1/20 0.38
CD274 Q9NZQ7 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1986931 1.00 ECE1 (0.43) ECE1TGFBR1ITGB2ICAM1ITGAL
SCHEMBL1096294 0.86 ECE1 (0.43) ECE1TGFBR1ITGB2ICAM1ITGAL
SCHEMBL8675912 0.84 ECE1 (0.42) ECE1TGFBR1ITGB2ICAM1ITGAL
SCHEMBL2514366 0.84 ECE1 (0.42) ECE1TGFBR1ITGB2ICAM1ITGAL
SCHEMBL1226550 0.83 ECE1 (0.41) ECE1TGFBR1ITGB2ICAM1ITGAL
SCHEMBL1226547 0.83 ECE1 (0.41) ECE1TGFBR1ITGB2ICAM1ITGAL
SCHEMBL7777341 0.83 ECE1 (0.41) ECE1TGFBR1ITGB2ICAM1ITGAL
SCHEMBL3146208 0.81 SMN1; SMN2 (0.46) CA2
SCHEMBL4968311 0.81 SMN1; SMN2 (0.46) CA2
SCHEMBL4392510 0.81 ECE1 (0.40) ECE1TGFBR1ITGB2ICAM1ITGAL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240366738-A1 MOLECULAR VACCINES FOR INFECTIOUS DISEASE AGILENT TECHNOLOGIES INC (US) 2024-11-07 US disclosed
US-11992518-B2 Molecular vaccines for infectious disease AGILENT TECHNOLOGIES, INC. (US) 2024-05-28 US disclosed
US-10968269-B1 MHC multimers in borrelia diagnostics and disease AGILENT TECHNOLOGIES, INC. (US) 2021-04-06 US disclosed
US-20210047383-A1 MHC Multimers in Borrelia Diagnostics and Disease DAKO DENMARK APS (DK) 2021-02-18 US disclosed
US-20200347103-A1 MHC MULTIMERS IN TUBERCULOSIS DIAGNOSTICS, VACCINE AND THERAPEUTICS AGILENT TECHNOLOGIES INC (US) 2020-11-05 US disclosed
US-10611818-B2 MHC multimers in tuberculosis diagnostics, vaccine and therapeutics AGILENT TECHNOLOGIES, INC. (US) 2020-04-07 US disclosed
US-20190314471-A1 MOLECULAR VACCINES FOR INFECTIOUS DISEASE AGILENT TECHNOLOGIES, INC. 2019-10-17 US disclosed
US-10369204-B2 Molecular vaccines for infectious disease DAKO DENMARK A/S (DK) 2019-08-06 US disclosed
US-20120258126-A1 Molecular Vaccines for Infectious Disease DAKO DENMARK A/S (DK) 2012-10-11 US disclosed
US-20110318380-A1 MHC Multimers in Cancer Vaccines and Immune Monitoring DAKO DENMARK A/S (DK) 2011-12-29 US disclosed
EP-2337795-A2 MHC MULTIMERS IN CANCER VACCINES AND IMMUNE MONITORING Dako Denmark A/S (DK) 2011-06-29 EP disclosed
EP-2254592-A2 MHC MULTIMERS IN BORRELIA DIAGNOSTICS AND DISEASE Dako Denmark A/S (DK) 2010-12-01 EP disclosed
EP-2197908-A2 MHC MULTIMERS IN TUBERCULOSIS DIAGNOSTICS, VACCINE AND THERAPEUTICS Dako Denmark A/S (DK) 2010-06-23 EP disclosed
WO-2010037402-A1 MOLECULAR VACCINES FOR INFECTIOUS DISEASE DAKO DENMARK A/S (DK) 2010-04-08 WO disclosed
WO-2010037395-A2 MHC MULTIMERS IN CANCER VACCINES AND IMMUNE MONITORING DAKO DENMARK A/S (DK) 2010-04-08 WO disclosed
WO-2010037397-A1 MHC MULTIMERS IN CMV IMMUNE MONITORING DAKO DENMARK A/S (DK) 2010-04-08 WO disclosed
WO-2009106073-A2 MHC MULTIMERS IN BORRELIA DIAGNOSTICS AND DISEASE DAKO DENMARK A/S (DK) 2009-09-03 WO disclosed
WO-2009039854-A2 MHC MULTIMERS IN TUBERCULOSIS DIAGNOSTICS, VACCINE AND THERAPEUTICS DAKO DENMARK A/S (DK) 2009-04-02 WO disclosed
WO-2007001399-A2 COMPOSITIONS, SPLICE VARIANTS AND METHODS RELATING TO CANCER SPECIFIC GENES AND PROTEINS DIADEXUS, INC. (US) 2007-01-04 WO disclosed
WO-2003020899-A2 COMPOSITIONS AND METHODS RELATING TO LUNG SPECIFIC GENES AND PROTEINS DIADEXUS, INC. (US) 2003-03-13 WO disclosed