Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGIR | P43119 | 18/20 | 0.73 |
| ▸ | PTGDR | Q13258 | 10/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7772431 | 1.00 | PTGIR (0.73) | PTGIRPTGDRCYP19A1 | |
| SCHEMBL7772454 | 0.85 | PTGIR (0.78) | PTGIRPTGDRCYP19A1 | |
| SCHEMBL7772453 | 0.85 | PTGIR (0.78) | PTGIRPTGDRCYP19A1 | |
| SCHEMBL7776672 | 0.85 | PTGIR (1.00) | PTGIRPTGDR | |
| SCHEMBL7776667 | 0.85 | PTGIR (1.00) | PTGIRPTGDR | |
| SCHEMBL7777416 | 0.81 | PTGIR (0.81) | PTGIRPTGDR | |
| SCHEMBL7777412 | 0.81 | PTGIR (0.81) | PTGIRPTGDR | |
| SCHEMBL9017258 | 0.77 | PTGIR (0.85) | PTGIRPTGDR | |
| SCHEMBL8414330 | 0.72 | CYP19A1 (0.50) | PTGIRCYP19A1 | |
| SCHEMBL8410999 | 0.72 | CYP19A1 (0.50) | PTGIRCYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0749424-B1 | NAPHTHALENE DERIVATIVES AS PROSTAGLANDIN I2 AGONISTS | FUJISAWA PHARMACEUTICAL CO (JP) | 2001-09-12 | — | — | EP | disclosed |
| US-5863918-A | HYPOTENSIVE AGENTS, ANTICOAGULANTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1999-01-26 | — | — | US | disclosed |
| US-5763489-A | ANTICOAGULANTS AND HYPOTENSIVE AGENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-06-09 | — | — | US | disclosed |
| WO-1995024393-A1 | NAPHTHALENE DERIVATIVES AS PROSTAGLANDIN I2 AGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-09-14 | — | — | WO | disclosed |