Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 6/20 | 0.47 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.42 |
| ▸ | TRPA1 | O75762 | 4/20 | 0.41 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GFER | P55789 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | TACR1 | P25103 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11678634 | 0.91 | TAAR1 (0.42) | TAAR1AOC3TRPA1RIPK1KDM4E | |
| SCHEMBL18389692 | 0.84 | TAAR1 (0.47) | TAAR1AOC3TRPA1RIPK1KDM4E | |
| SCHEMBL4267109 | 0.82 | TAAR1 (0.45) | TAAR1AOC3TRPA1RIPK1KDM4E | |
| SCHEMBL3157144 | 0.81 | HTR2A (0.41) | TAAR1 | |
| SCHEMBL6576657 | 0.77 | TAAR1 (0.40) | TAAR1AOC3TRPA1RIPK1 | |
| SCHEMBL11313458 | 0.74 | TAAR1 (0.54) | TAAR1AOC3TRPA1RIPK1KDM4E | |
| SCHEMBL9230452 | 0.73 | TAAR1 (0.48) | TAAR1AOC3TRPA1RIPK1KDM4E | |
| SCHEMBL10902064 | 0.73 | TAAR1 (0.37) | TAAR1AOC3TRPA1RIPK1ALDH1A1 | |
| SCHEMBL4262737 | 0.72 | TAAR1 (0.52) | TAAR1AOC3TRPA1RIPK1KDM4E | |
| SCHEMBL6268405 | 0.72 | TAAR1 (0.52) | TAAR1AOC3TRPA1RIPK1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1126816-A1 | METHOD OF USING AN ARALKYLSILOXANE | GENERAL ELECTRIC COMPANY (US) | 2001-08-29 | — | — | EP | disclosed |
| WO-2000027348-A1 | METHOD OF USING AN ARALKYLSILOXANE | GENERAL ELECTRIC COMPANY (US) | 2000-05-18 | — | — | WO | disclosed |