Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 4/20 | 0.40 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.36 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7777478 | 0.77 | TAAR1 (0.47) | TAAR1TRPA1AOC3RIPK1 | |
| SCHEMBL18389692 | 0.77 | TAAR1 (0.47) | TAAR1TRPA1AOC3RIPK1 | |
| SCHEMBL11678634 | 0.76 | TAAR1 (0.42) | TAAR1TRPA1AOC3LMNARIPK1 | |
| SCHEMBL4267109 | 0.75 | TAAR1 (0.45) | TAAR1TRPA1AOC3RIPK1 | |
| SCHEMBL17453236 | 0.69 | TAAR1 (0.61) | TAAR1TRPA1AOC3LMNARIPK1 | |
| Benzene SCHEMBL5290987 | 0.69 | TAAR1 (0.61) | TAAR1TRPA1AOC3LMNARIPK1 | |
| SCHEMBL4443642 | 0.69 | TAAR1 (0.61) | TAAR1TRPA1AOC3LMNARIPK1 | |
| SCHEMBL136376 | 0.69 | TAAR1 (0.61) | TAAR1TRPA1AOC3LMNARIPK1 | |
| SCHEMBL8767509 | 0.68 | TAAR1 (0.45) | TAAR1TRPA1AOC3LMNARIPK1 | |
| SCHEMBL11313458 | 0.68 | TAAR1 (0.54) | TAAR1TRPA1AOC3RIPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1035154-B1 | Use of silicone polyethers with arylalkyl groups in personal care products | DOW CORNING (US) | 2004-04-28 | — | — | EP | disclosed |
| US-6133370-A | A POLYETHERSILOXANE COPOLYMER WHEREIN THE TRIALKYLSILANOL ENDCAPPED POLYSILOXANE CONTAINING AN ARYLALKYL GROUP IN ITS MONOMER AND A LINKER GROUP LINKS THE COPOLYMER; USEFUL FOR PREPARING PERSONAL CARE PRODUCTS FOR HAIR, SKIN AND UNDERARM | DOW CORNING CORPORATION (US) | 2000-10-17 | — | — | US | disclosed |
| EP-1035154-A2 | Silicone polyethers with arylalkyl groups | DOW CORNING CORPORATION (US) | 2000-09-13 | — | — | EP | disclosed |