SCHEMBL777750

SCHEMBL777750

Fc1ccc(-c2cccc(F)c2)cc1

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 3/20 0.71
ESR2 Q92731 1/20 0.71
CYP11B2 P19099 2/20 0.55
CYP3A4 P08684 2/20 0.55
CYP17A1 P05093 1/20 0.55
CYP11B1 P15538 1/20 0.55
AGXT P21549 1/20 0.52
PTPN1 P18031 1/20 0.52
HTR1A P08908 1/20 0.47
HTR7 P34969 1/20 0.47
NFE2L2 Q16236 1/20 0.46
MAP4K4 O95819 1/20 0.46
DCLRE1B Q9H816 1/20 0.44
TNKS2 Q9H2K2 1/20 0.44
CYP2C9 P11712 1/20 0.44
HSD17B1 P14061 1/20 0.44
HSD17B2 P37059 1/20 0.44
ACHE P22303 1/20 0.44
MEN1 O00255 1/20 0.44
ESR1 P03372 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Sulfur Dioxide SCHEMBL29045638 0.91 TAAR1 (0.61) TAAR1ESR2CYP11B2CYP3A4CYP17A1
SCHEMBL15605009 0.90 TAAR1 (0.71) TAAR1ESR2CYP11B2CYP3A4CYP17A1
SCHEMBL26821707 0.89 TAAR1 (0.56) TAAR1ESR2CYP3A4AGXTHTR1A
SCHEMBL28269989 0.89 TAAR1 (0.56) TAAR1ESR2CYP3A4AGXTHTR1A
SCHEMBL198702 0.89 TAAR1 (0.68) TAAR1ESR2CYP11B2CYP3A4CYP17A1
Biphenyl SCHEMBL25183774 0.86 TAAR1 (0.67) TAAR1ESR2CYP11B2CYP3A4CYP17A1
SCHEMBL29451178 0.86 TAAR1 (0.67) TAAR1ESR2CYP11B2CYP3A4CYP17A1
SCHEMBL200605 0.86 TAAR1 (0.67) TAAR1ESR2CYP11B2CYP3A4CYP17A1
SCHEMBL16605626 0.86 TAAR1 (0.65) TAAR1ESR2CYP11B2CYP3A4CYP17A1
SCHEMBL16605628 0.86 TAAR1 (0.65) TAAR1ESR2CYP11B2CYP3A4CYP17A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4695240-A2 CYCLIC VINYL SULFONE WRN INHIBITORS Nimbus Wadjet, Inc. (US) 2026-02-18 EP disclosed
WO-2024215923-A2 CYCLIC VINYL SULFONE WRN INHIBITORS NIMBUS WADJET, INC. (US) 2024-10-17 WO disclosed
US-12100809-B2 Non-aqueous liquid electrolyte and non-aqueous liquid electrolyte secondary battery MITSUBISHI CHEMICAL CORPORATION (JP) 2024-09-24 US disclosed
WO-2024014851-A1 NOVEL PURINE DERIVATIVE COMPOUNDS AS HIF-1 PROTEIN INHIBITOR 주식회사 넥스트젠바이오사이언스 2024-01-18 WO disclosed
US-20230322725-A1 INHIBITORS FOR THE B-CATENIN/B-CELL LYMPHOMA 9 (BCL9) PROTEIN-PROTEIN INTERACTION H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE, INC. 2023-10-12 US disclosed
CN-115557913-A Benzoazaheterocyclic compounds and application thereof in medicines 广东东阳光药业有限公司 2023-01-03 CN disclosed
CN-114761000-A Substituted 1, 6-naphthyridine inhibitors of CDK5 金翅雀生物公司 2022-07-15 CN disclosed
US-20220149436-A1 NON-AQUEOUS LIQUID ELECTROLYTE AND NON-AQUEOUS LIQUID ELECTROLYTE SECONDARY BATTERY MITSUBISHI CHEMICAL CORPORATION (JP) 2022-05-12 US disclosed
US-11283107-B2 Non-aqueous liquid electrolyte and non-aqueous liquid electrolyte secondary battery MITSUBISHI CHEMICAL CORPORATION (JP) 2022-03-22 US disclosed
EP-3621141-A1 NON-AQUEOUS LIQUID ELECTROLYTE AND NON-AQUEOUS LIQUID ELECTROLYTE SECONDARY BATTERY MITSUBISHI CHEMICAL CORPORATION (JP) 2020-03-11 EP disclosed
US-20090325065-A1 NON-AQUEOUS LIQUID ELECTROLYTE AND NON-AQUEOUS LIQUID ELECTROLYTE SECONDARY BATTERY MITSUBISHI CHEMICAL CORPORATION (JP) 2009-12-31 US disclosed
US-7623214-B2 Liquid crystal materials DOW CORNING CORPORATION (US) 2009-11-24 US disclosed
EP-1713880-B1 LIQUID CRYSTAL MATERIALS DOW CORNING (US) 2009-10-28 EP disclosed
CN-101432923-A Nonaqueous electrolyte solution and nonaqueous electrolyte secondary battery MITSUBISHI CHEM CORP (JP) 2009-05-13 CN disclosed
US-20090115957-A1 Liquid crystal materials DOW SILICONES CORPORATION 2009-05-07 US disclosed
EP-2012386-A1 NONAQUEOUS ELECTROLYTE SOLUTION AND NONAQUEOUS ELECTROLYTE SECONDARY BATTERY Mitsubishi Chemical Corporation (JP) 2009-01-07 EP disclosed
EP-1713880-A1 LIQUID CRYSTAL MATERIALS Dow Corning Corporation (US) 2006-10-25 EP disclosed
WO-2005075603-A1 LIQUID CRYSTAL MATERIALS DOW CORNING CORPORATION (US) 2005-08-18 WO disclosed
US-6242654-B1 REACTING A PHENOLATE COMPOUND WITH AN ORGANIC FLUORINATING AGENT TO PREPARE A FLUORINE SUBSTITUTED AROMATIC COMPOUND MITSUI CHEMICALS, INC. (JP) 2001-06-05 US disclosed
EP-1013629-A1 Preparation process of fluorine subsituted aromatic compound Mitsui Chemicals, Inc. (JP) 2000-06-28 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230322725-A1 INHIBITORS FOR THE B-CATENIN/B-CELL LYMPHOMA 9 (BCL9) PROTEIN-PROTEIN INTERACTION BCL9, BCL9L, BCL3 TAAR1 4863/4885ESR2 1703/4885CYP11B2 3220/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.