Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC25A | P30304 | 3/20 | 0.58 |
| ▸ | CDC25B | P30305 | 1/20 | 0.58 |
| ▸ | VDR | P11473 | 6/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | PGR | P06401 | 1/20 | 0.48 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.48 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.48 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.48 |
| ▸ | DRD3 | P35462 | 1/20 | 0.48 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7777809 | 1.00 | CDC25A (0.58) | CDC25ACDC25BVDRMEN1KMT2A | |
| SCHEMBL7777813 | 1.00 | CDC25A (0.58) | CDC25ACDC25BVDRMEN1KMT2A | |
| SCHEMBL25313329 | 0.90 | CDC25A (0.54) | CDC25ACDC25BVDRMEN1KMT2A | |
| SCHEMBL25313334 | 0.90 | CDC25A (0.54) | CDC25ACDC25BVDRMEN1KMT2A | |
| SCHEMBL6720175 | 0.85 | VDR (0.62) | CDC25ACDC25BVDRMAPTPGR | |
| SCHEMBL6736404 | 0.84 | VDR (0.70) | CDC25ACDC25BVDRMAPTPGR | |
| SCHEMBL24571965 | 0.84 | VDR (0.70) | CDC25ACDC25BVDRMAPTPGR | |
| SCHEMBL13849336 | 0.84 | VDR (0.70) | CDC25ACDC25BVDRMAPTPGR | |
| SCHEMBL26324497 | 0.84 | VDR (0.70) | CDC25ACDC25BVDRMAPTPGR | |
| SCHEMBL17888103 | 0.84 | VDR (0.70) | CDC25ACDC25BVDRMAPTPGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0854139-B1 | Vitamin D3 derivative and production process thereof | TEIJIN LTD (JP) | 2001-09-05 | — | — | EP | disclosed |
| US-6177586-B1 | USEFUL AS A PHARMACEUTICAL SUCH AS AN AGENT FOR PROMOTING BONE FORMATION, AN AGENT FOR SUPPRESSING PROLIFERATION OF TUMOR CELLS, AN AGENT FOR HIGH CALCIUM BLOOD DISEASES, AND AN IMMUNOSUPPRESSION AGENT | TEIJIN LIMITED (JP) | 2001-01-23 | — | — | US | disclosed |
| US-5986112-A | STEROID DERIVATIVES AS ANTITUMOR AGENTS AND BLOOD METAL CONCENTRATES | TEIJIN LIMITED (JP) | 1999-11-16 | — | — | US | disclosed |
| EP-0854139-A2 | Vitamin D3 derivative and production process thereof | TEIJIN LIMITED (JP) | 1998-07-22 | — | — | EP | disclosed |
| EP-0854138-A2 | Vitamin D3 derivative and production process thereof | TEIJIN LIMITED (JP) | 1998-07-22 | — | — | EP | disclosed |
| EP-0712843-A1 | VITAMIN D3 DERIVATIVE AND PROCESS FOR PRODUCING THE SAME | TEIJIN LIMITED (JP) | 1996-05-22 | — | — | EP | disclosed |