Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.62 |
| ▸ | RAB9A | P51151 | 1/20 | 0.62 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.56 |
| ▸ | DPP4 | P27487 | 1/20 | 0.56 |
| ▸ | TYR | P14679 | 4/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | SLC28A3 | Q9HAS3 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 2/20 | 0.48 |
| ▸ | CA1 | P00915 | 2/20 | 0.48 |
| ▸ | CA9 | Q16790 | 2/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL941510 | 0.88 | NPC1 (0.65) | NPC1RAB9AAKR1B1DPP4TYR | |
| SCHEMBL4636284 | 0.87 | NPC1 (0.64) | NPC1RAB9AAKR1B1DPP4TYR | |
| SCHEMBL941333 | 0.86 | NPC1 (0.63) | NPC1RAB9AAKR1B1DPP4TYR | |
| SCHEMBL941045 | 0.86 | NPC1 (0.70) | NPC1RAB9AAKR1B1DPP4TYR | |
| SCHEMBL7778005 | 0.85 | NPC1 (0.62) | NPC1RAB9AAKR1B1DPP4TYR | |
| SCHEMBL7777981 | 0.84 | SLC28A3 (0.50) | AKR1B1DPP4TYRPOLBSLC28A3 | |
| SCHEMBL7780286 | 0.83 | NPC1 (0.59) | NPC1RAB9AAKR1B1DPP4TYR | |
| SCHEMBL28346617 | 0.82 | NPC1 (0.74) | NPC1RAB9AAKR1B1DPP4TYR | |
| SCHEMBL4635640 | 0.82 | NPC1 (0.68) | NPC1RAB9AAKR1B1DPP4TYR | |
| SCHEMBL943281 | 0.80 | NPC1 (0.57) | NPC1RAB9AAKR1B1DPP4TYR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0649648-B1 | Skin whitening agents containing glycosides | SHISEIDO CO LTD (JP) | 2001-09-19 | — | — | EP | disclosed |