Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.70 |
| ▸ | RAB9A | P51151 | 1/20 | 0.70 |
| ▸ | TYR | P14679 | 2/20 | 0.61 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.60 |
| ▸ | DPP4 | P27487 | 1/20 | 0.60 |
| ▸ | APP | P05067 | 1/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | SLC28A3 | Q9HAS3 | 1/20 | 0.54 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL940963 | 0.91 | APP (0.62) | NPC1RAB9ATYRAKR1B1DPP4 | |
| SCHEMBL941510 | 0.89 | NPC1 (0.65) | NPC1RAB9ATYRAKR1B1DPP4 | |
| SCHEMBL4636284 | 0.88 | NPC1 (0.64) | NPC1RAB9ATYRAKR1B1DPP4 | |
| SCHEMBL28346617 | 0.87 | NPC1 (0.74) | NPC1RAB9ATYRAKR1B1DPP4 | |
| SCHEMBL4635640 | 0.87 | NPC1 (0.68) | NPC1RAB9ATYRAKR1B1DPP4 | |
| SCHEMBL941333 | 0.87 | NPC1 (0.63) | NPC1RAB9ATYRAKR1B1DPP4 | |
| SCHEMBL7777937 | 0.86 | NPC1 (0.62) | NPC1RAB9ATYRAKR1B1DPP4 | |
| SCHEMBL7778005 | 0.86 | NPC1 (0.62) | NPC1RAB9ATYRAKR1B1DPP4 | |
| SCHEMBL4635920 | 0.85 | SLC28A3 (0.58) | NPC1RAB9ATYRAKR1B1DPP4 | |
| SCHEMBL7780286 | 0.83 | NPC1 (0.59) | NPC1RAB9ATYRAKR1B1DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1932514-B1 | PHARMACEUTICAL PREPARATION FOR EXTERNAL APPLICATION TO SKIN COMPRISING PHOSPHORYLATED SUGAR | EZAKI GLICO CO (JP) | 2018-11-14 | — | — | EP | disclosed |
| US-20140023602-A1 | EXTERNAL PREPARATION FOR SKIN CONTAINING A PHOSPHORYLATED SACCHARIDE | EZAKI GLICO CO., LTD. (JP) | 2014-01-23 | — | — | US | disclosed |
| US-20110014141-A1 | TOPICAL AGENT FOR DERMATOLOGICAL USE | DSM IP ASSETS B.V. (NL) | 2011-01-20 | — | — | US | disclosed |
| US-20080274068-A1 | External Preparation for Skin Containing a Phosphorlated Saccharide | EZAKI GLICO CO., LTD. (JP) | 2008-11-06 | — | — | US | disclosed |
| EP-1932514-A1 | PHARMACEUTICAL PREPARATION FOR EXTERNAL APPLICATION TO SKIN COMPRISING PHOSPHORYLATED SUGAR | Ezaki Glico Co., Ltd. (JP) | 2008-06-18 | — | — | EP | disclosed |
| EP-1859835-A2 | Topical agent for dermatological use containing 4-hydroxyphenyl-alpha-D-glucopyranoside | PENTAPHARM Ltd. (CH) | 2007-11-28 | — | — | EP | disclosed |
| US-20030198610-A1 | Topical agent for dermatological use | DSM IP ASSETS B.V. (NL) | 2003-10-23 | — | — | US | disclosed |
| EP-0649648-B1 | Skin whitening agents containing glycosides | SHISEIDO CO LTD (JP) | 2001-09-19 | — | — | EP | disclosed |
| US-5700784-A | GLYCOSIDES OF HYDROXYSALICYLIC ACID AND/OR GLYCOSIDES OF ESTERS OF HYDROXYSALICYLIC ACID; EXCELLENT WHITENING EFFECT AND SKIN CARE EFFECT | SHISEIDO CO., LTD. (JP) | 1997-12-23 | — | — | US | disclosed |
| EP-0649648-A2 | Skin whitening agents containing glycosides | SHISEIDO COMPANY LIMITED (JP) | 1995-04-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110014141-A1 | TOPICAL AGENT FOR DERMATOLOGICAL USE | GALE, ALPP, UGGT1 | NPC1 2633/4885RAB9A 4832/4885TYR 9/4885 |
| US-20140023602-A1 | EXTERNAL PREPARATION FOR SKIN CONTAINING A PHOSPHORYLATED SACCHARIDE | SI, CUTA, CD44 | NPC1 4440/4885RAB9A 4230/4885TYR 149/4885 |
| US-20030198610-A1 | Topical agent for dermatological use | GALE, UGGT1, UGDH | NPC1 2969/4885RAB9A 4806/4885TYR 6/4885 |
| US-20080274068-A1 | External Preparation for Skin Containing a Phosphorlated Saccharide | CUTA, SI, CD44 | NPC1 4374/4885RAB9A 4065/4885TYR 113/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.