Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXA2R | P21731 | 9/20 | 0.71 |
| ▸ | TBXAS1 | P24557 | 10/20 | 0.53 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8120060 | 0.91 | TBXA2R (0.62) | TBXA2RTBXAS1HDAC8 | |
| SCHEMBL7778006 | 0.89 | TBXA2R (0.66) | TBXA2RTBXAS1HDAC8 | |
| SCHEMBL9249635 | 0.85 | TBXA2R (0.75) | TBXA2RTBXAS1HDAC8 | |
| SCHEMBL7771697 | 0.84 | TBXA2R (0.78) | TBXA2RTBXAS1HDAC8 | |
| Terutroban SCHEMBL1896773 | 0.83 | TBXA2R (1.00) | TBXA2RTBXAS1HDAC8 | |
| Terutroban SCHEMBL43629 | 0.83 | TBXA2R (1.00) | TBXA2RTBXAS1HDAC8 | |
| Terutroban SCHEMBL29378918 | 0.83 | TBXA2R (1.00) | TBXA2RTBXAS1HDAC8 | |
| SCHEMBL7777976 | 0.83 | TBXA2R (0.52) | TBXA2RTBXAS1HDAC8 | |
| SCHEMBL9246542 | 0.82 | TBXA2R (0.79) | TBXA2RTBXAS1HDAC8 | |
| SCHEMBL7776200 | 0.82 | TBXA2R (0.76) | TBXA2RTBXAS1HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0864561-B1 | Benzenesulfonylamine derivatives,process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 2001-09-05 | — | — | EP | disclosed |
| EP-0864561-A1 | Benzenesulfonylamine derivatives,process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1998-09-16 | — | — | EP | disclosed |