Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXA2R | P21731 | 8/20 | 0.66 |
| ▸ | TBXAS1 | P24557 | 11/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8116712 | 0.92 | TBXA2R (0.57) | TBXA2RTBXAS1HDAC8 | |
| SCHEMBL7777970 | 0.89 | TBXA2R (0.71) | TBXA2RTBXAS1HDAC8 | |
| SCHEMBL7771855 | 0.89 | TBXA2R (0.68) | TBXA2RTBXAS1HDAC8 | |
| SCHEMBL7779019 | 0.86 | TBXA2R (0.69) | TBXA2RTBXAS1HDAC8 | |
| SCHEMBL7776177 | 0.84 | TBXA2R (0.61) | TBXA2RTBXAS1HDAC8 | |
| SCHEMBL8115014 | 0.82 | TBXA2R (0.57) | TBXA2RTBXAS1HDAC8 | |
| SCHEMBL8120060 | 0.81 | TBXA2R (0.62) | TBXA2RTBXAS1HDAC8 | |
| SCHEMBL8113863 | 0.81 | TBXA2R (0.59) | TBXA2RTBXAS1HDAC8 | |
| SCHEMBL7776165 | 0.80 | TBXA2R (0.56) | TBXA2RTBXAS1 | |
| Terutroban SCHEMBL43629 | 0.80 | TBXA2R (1.00) | TBXA2RTBXAS1HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0864561-B1 | Benzenesulfonylamine derivatives,process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 2001-09-05 | — | — | EP | disclosed |
| US-6013667-A | Benzenesulfonylamine compounds, process for preparing them and pharmaceutical compositions | ADIR ET COMPAGNIE (FR) | 2000-01-11 | — | — | US | disclosed |
| EP-0864561-A1 | Benzenesulfonylamine derivatives,process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1998-09-16 | — | — | EP | disclosed |