Phenethylamine

Phenethylamine

SCHEMBL77780

NCCc1ccccc1.O=S(=O)(F)F

nearest known ligand 0.73

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 2/20 0.73
CYP2A6 P11509 1/20 0.73
SMN1; SMN2 Q16637 1/20 0.73
TAAR1 Q96RJ0 1/20 0.73
LOXL2 Q9Y4K0 1/20 0.73
HTR6 P50406 5/20 0.62
F2 P00734 2/20 0.61
TMPRSS4 Q9NRS4 2/20 0.61
TP53 P04637 1/20 0.61
CYP1A2 P05177 1/20 0.61
CYP2D6 P10635 1/20 0.61
TSHR P16473 1/20 0.61
FAAH O00519 1/20 0.52
PRSS1 P07477 1/20 0.52
PRSS2 P07478 1/20 0.52
ELANE P08246 1/20 0.52
PRTN3 P24158 1/20 0.52
PRSS3 P35030 1/20 0.52
MAOA P21397 1/20 0.52
CA1 P00915 2/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phenethylamine SCHEMBL25972 0.98 HTR2A (0.70) HTR2ACYP2A6SMN1; SMN2TAAR1LOXL2
Phenethylamine SCHEMBL3721983 0.91 HTR2A (0.67) HTR2ACYP2A6SMN1; SMN2TAAR1LOXL2
Phenethylamine SCHEMBL11319344 0.86 HTR2A (0.73) HTR2ACYP2A6SMN1; SMN2TAAR1LOXL2
Phenethylamine SCHEMBL27616397 0.86 HTR2A (0.73) HTR2ACYP2A6SMN1; SMN2TAAR1LOXL2
Phenethylamine SCHEMBL968 0.85
Phenethylamine SCHEMBL1799333 0.85 HTR2A (1.00) HTR2ACYP2A6SMN1; SMN2TAAR1LOXL2
Phenethylamine SCHEMBL27634208 0.85 HTR2A (1.00) HTR2ACYP2A6SMN1; SMN2TAAR1LOXL2
Phenethylamine SCHEMBL1332244 0.85
Phenethylamine SCHEMBL1331271 0.85
Phenethylamine SCHEMBL1330939 0.85

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 286 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101304780-B Apparatus containing active substance from tissue 史密夫及内修公开有限公司 2016-12-07 CN claimed
EP-1933926-B1 APPARATUS WITH ACTIVES FROM TISSUE SMITH & NEPHEW (GB) 2012-10-24 EP claimed
US-8257327-B2 Wound cleansing apparatus with actives SMITH & NEPHEW PLC (GB) 2012-09-04 US claimed
EP-2251059-A1 Apparatus with actives from tissue Smith & Nephew, PLC (GB) 2010-11-17 EP claimed
US-20100249733-A9 APPARATUS WITH ACTIVES FROM TISSUE SMITH & NEPHEW PLC (GB) 2010-09-30 US claimed
EP-1562668-B1 Medical apparatus for irrigating wounds SMITH & NEPHEW (GB) 2009-12-02 EP claimed
US-20090143753-A1 APPARATUS WITH ACTIVES FROM TISSUE SMITH & NEPHEW PLC (GB) 2009-06-04 US claimed
US-7524315-B2 Apparatus for aspirating, irrigating and cleansing wounds SMITH & NEPHEW PLC (GB) 2009-04-28 US claimed
EP-1933926-A1 APPARATUS WITH ACTIVES FROM TISSUE Smith & Nephew, PLC (GB) 2008-06-25 EP claimed
WO-2007031765-A1 APPARATUS WITH ACTIVES FROM TISSUE SMITH & NEPHEW, PLC (GB) 2007-03-22 WO claimed
US-20060155260-A1 Apparatus for aspirating, irrigating and cleansing wounds SMITH & NEPHEW PLC (GB) 2006-07-13 US claimed
EP-1562668-A1 APPARATUS FOR ASPIRATING, IRRIGATING AND CLEANSING WOUNDS Smith & Nephew PLC (GB) 2005-08-17 EP claimed
US-20050164945-A1 Endotheliase-1 ligands DENDREON CORPORATION 2005-07-28 US claimed
WO-2005041631-A2 ENDOTHELIASE-1 LIGANDS DYAX CORP. (US) 2005-05-12 WO claimed
WO-2004037334-A1 APPARATUS FOR ASPIRATING, IRRIGATING AND CLEANSING WOUNDS SMITH & NEPHEW PLC (GB) 2004-05-06 WO claimed
US-20260008805-A1 ADENOSINE ANALOGS FOR THE TREATMENT OF DISEASE BIOINTERVENE INC (US) 2026-01-08 US disclosed
US-12378543-B2 Compositions for hemolysis and coagulation regulation and stabilization of extracellular vesicles STRECK LLC (US) 2025-08-05 US disclosed
WO-2000069908-A1 INTERACTION BETWEEN THE VHL TUMOUR SUPPRESSOR AND HYPOXIA INDUCIBLE FACTOR, AND ASSAY METHODS RELATING THERETO ISIS INNOVATION LIMITED (GB) 2000-11-23 WO disclosed
WO-2000062068-A1 METHOD TO TYPE PRION PROTEINS D-GEN LIMITED (GB) 2000-10-19 WO disclosed
WO-1999049887-A1 USE OF PROTEASE INHIBITORS FOR TREATING SKIN WOUNDS BIOTECH AUSTRALIA PTY. LIMITED (AU) 1999-10-07 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260008805-A1 ADENOSINE ANALOGS FOR THE TREATMENT OF DISEASE ADORA2B, ADORA2A, ADORA1 HTR2A 168/4885CYP2A6 463/4885SMN1; SMN2 509/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.