SCHEMBL7778162

SCHEMBL7778162

CCCCCCCCCOc1ccc(C(=O)Oc2ccc(C(=O)OC(C)CCCCCC)c(F)c2)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 3/20 0.50
LMNA P02545 3/20 0.50
NFKB1 P19838 3/20 0.50
NFKB2 Q00653 3/20 0.50
RELA Q04206 3/20 0.50
SMN1; SMN2 Q16637 2/20 0.50
TSHR P16473 2/20 0.48
CYP1A2 P05177 1/20 0.48
CYP3A4 P08684 1/20 0.48
CYP2D6 P10635 1/20 0.48
CYP2C9 P11712 1/20 0.48
CYP2C19 P33261 1/20 0.48
ALDH1A1 P00352 1/20 0.47
TP53 P04637 1/20 0.45
MAPT P10636 2/20 0.45
KMT2A Q03164 2/20 0.45
PLA2G4B P0C869 2/20 0.44
POLB P06746 1/20 0.44
PRSS1 P07477 1/20 0.43
ACR P10323 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9628503 1.00 NPC1 (0.50) NPC1LMNANFKB1NFKB2RELA
SCHEMBL8608309 0.97 RARB (0.48) NPC1LMNANFKB1NFKB2RELA
SCHEMBL8609010 0.97 RARB (0.48) NPC1LMNANFKB1NFKB2RELA
SCHEMBL9627223 0.97 RARB (0.48) NPC1LMNANFKB1NFKB2RELA
SCHEMBL8015772 0.94 RARB (0.45) NPC1LMNANFKB1NFKB2RELA
SCHEMBL10633030 0.93 RARB (0.48) NPC1LMNANFKB1NFKB2RELA
SCHEMBL9626606 0.93 NPC1 (0.51) NPC1LMNANFKB1NFKB2RELA
SCHEMBL8013726 0.93 RARB (0.48) NPC1LMNANFKB1NFKB2RELA
SCHEMBL8013531 0.92 RARB (0.45) NPC1LMNANFKB1NFKB2RELA
SCHEMBL7756723 0.91 TSHR (0.47) NPC1LMNANFKB1NFKB2RELA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-10279534-A None JP disclosed
EP-0878460-B1 Racemic compound and anti-ferroelectric liquid crystal composition containing the compound MITSUBISHI GAS CHEMICAL CO (JP) 2001-09-19 EP disclosed
US-5980780-A SMALL SPONTANEOUS POLARIZATION AND FAST RESPONSE; FOR HIGH QUALITY LIQUID CRYSTAL DISPLAY DEVICE MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 1999-11-09 US disclosed
EP-0878460-A1 Racemic compound and anti-ferroelectric liquid crystal composition containing the compound MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 1998-11-18 EP disclosed
JP-H10279534-A RACEMIC COMPOUND AND ANTIFERROELECTRIC LIQUID CRYSTAL COMPOSITION CONTAINING THE SAME MITSUBISHI GAS CHEM CO INC 1998-10-20 JP disclosed