SCHEMBL8015772

SCHEMBL8015772

CCCCCCCCCOc1ccc(-c2ccc(C(=O)Oc3ccc(C(=O)OC(C)CCCCOC)c(F)c3)cc2)cc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RARB P10826 5/20 0.45
NPC1 O15118 3/20 0.44
LMNA P02545 3/20 0.44
NFKB1 P19838 3/20 0.44
NFKB2 Q00653 3/20 0.44
RELA Q04206 3/20 0.44
SMN1; SMN2 Q16637 2/20 0.44
RARA P10276 1/20 0.44
TSHR P16473 2/20 0.43
CYP1A2 P05177 1/20 0.43
CYP3A4 P08684 1/20 0.43
CYP2D6 P10635 1/20 0.43
CYP2C9 P11712 1/20 0.43
CYP2C19 P33261 1/20 0.43
ALDH1A1 P00352 1/20 0.42
MAPT P10636 2/20 0.40
TP53 P04637 1/20 0.40
KMT2A Q03164 1/20 0.40
PPARG P37231 2/20 0.40
POLB P06746 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8013531 0.98 RARB (0.45) RARBNPC1LMNANFKB1NFKB2
SCHEMBL8608309 0.96 RARB (0.48) RARBNPC1LMNANFKB1NFKB2
SCHEMBL9627223 0.96 RARB (0.48) RARBNPC1LMNANFKB1NFKB2
SCHEMBL8609010 0.96 RARB (0.48) RARBNPC1LMNANFKB1NFKB2
SCHEMBL7778162 0.94 NPC1 (0.50) RARBNPC1LMNANFKB1NFKB2
SCHEMBL9628503 0.94 NPC1 (0.50) RARBNPC1LMNANFKB1NFKB2
SCHEMBL10633030 0.93 RARB (0.48) RARBNPC1LMNANFKB1NFKB2
SCHEMBL8013726 0.92 RARB (0.48) RARBNPC1LMNANFKB1NFKB2
SCHEMBL7756723 0.91 TSHR (0.47) RARBNPC1LMNANFKB1NFKB2
SCHEMBL7758468 0.91 TSHR (0.47) RARBNPC1LMNANFKB1NFKB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6103517-A ECONOMICAL, SIMPLE PRODUCTION OF SECONDARY ALCOHOL CONTAINING ASSYMETRIC CARBON HAVING SUBSTITUTED METHYL GROUP AND HAVING ALKOXY AS TERMINAL GROUP BY ASSYMETRIC TRANSESTERIFICATION USING VINYL PROPIONATE AND LIPASE FROM CANDIDA ANTARCIA MITSUBISHI GAS CHEMICAL COMPANY (JP) 2000-08-15 US disclosed