Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | PKM | P14618 | 2/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL944640 | 0.77 | MEN1 (0.39) | ALDH1A1SRD5A2MEN1KMT2APKM | |
| SCHEMBL6538714 | 0.74 | ALDH1A1 (0.37) | ALDH1A1SRD5A2MEN1KMT2APKM | |
| SCHEMBL6538716 | 0.74 | ALDH1A1 (0.37) | ALDH1A1SRD5A2MEN1KMT2APKM | |
| SCHEMBL4146905 | 0.74 | ALDH1A1 (0.37) | ALDH1A1SRD5A2MEN1KMT2APKM | |
| SCHEMBL5695058 | 0.72 | ALDH1A1 (0.39) | ALDH1A1SRD5A2MEN1KMT2APKM | |
| SCHEMBL10106489 | 0.72 | ALDH1A1 (0.46) | ALDH1A1SRD5A2MEN1KMT2APKM | |
| SCHEMBL2984291 | 0.72 | ALDH1A1 (0.45) | ALDH1A1SRD5A2MEN1KMT2APKM | |
| SCHEMBL21561629 | 0.72 | ALDH1A1 (0.44) | ALDH1A1SRD5A2MEN1KMT2APKM | |
| SCHEMBL5207902 | 0.72 | ALDH1A1 (0.36) | ALDH1A1SRD5A2MEN1KMT2APKM | |
| SCHEMBL8904981 | 0.72 | ALDH1A1 (0.36) | ALDH1A1SRD5A2MEN1KMT2APKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1121372-A1 | ADENINE DERIVATIVES | Pfizer Limited (GB) | 2001-08-08 | — | — | EP | claimed |
| WO-2000023457-A1 | ADENINE DERIVATIVES | PFIZER LIMITED (GB) | 2000-04-27 | — | — | WO | claimed |