Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.58 |
| ▸ | PKM | P14618 | 1/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.58 |
| ▸ | NAAA | Q02083 | 3/20 | 0.50 |
| ▸ | EPHX1 | P07099 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | SIRT2 | Q8IXJ6 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | SIRT1 | Q96EB6 | 2/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Carbamic Acid SCHEMBL7778361 | 0.90 | NAAA (0.49) | SMN1; SMN2CYP1A2CYP2D6PKMNPSR1 | |
| SCHEMBL7775519 | 0.80 | CYP1A2 (0.71) | SMN1; SMN2CYP1A2CYP2D6PKMNPSR1 | |
| SCHEMBL7777226 | 0.78 | CYP1A2 (0.68) | SMN1; SMN2CYP1A2CYP2D6PKMNPSR1 | |
| SCHEMBL7775738 | 0.77 | CYP1A2 (0.62) | SMN1; SMN2CYP1A2CYP2D6PKMNPSR1 | |
| Felbamate SCHEMBL34947 | 0.76 | CYP1A2 (1.00) | SMN1; SMN2CYP1A2CYP2D6PKMNPSR1 | |
| Felbamate SCHEMBL2946508 | 0.76 | CYP1A2 (1.00) | SMN1; SMN2CYP1A2CYP2D6PKMNPSR1 | |
| Felbamate SCHEMBL17597519 | 0.75 | CYP1A2 (0.96) | SMN1; SMN2CYP1A2CYP2D6PKMNPSR1 | |
| Felbamate SCHEMBL7153063 | 0.75 | CYP1A2 (0.96) | SMN1; SMN2CYP1A2CYP2D6PKMNPSR1 | |
| SCHEMBL13176888 | 0.74 | CYP1A2 (0.80) | SMN1; SMN2CYP1A2CYP2D6PKMNPSR1 | |
| SCHEMBL7778358 | 0.73 | SMN1; SMN2 (0.64) | SMN1; SMN2CYP1A2CYP2D6PKMNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0820440-B1 | NOVEL CARBAMATE COMPOUNDS HAVING N-SUBSTITUTED THIOCARBAMOYL GROUP AND PROCESS FOR PREPARING THE SAME | SK CORP (KR) | 2001-08-29 | — | — | EP | disclosed |
| US-5817858-A | Carbamate compounds having N-substituted thiocarbamoyl group and process for preparing the same | YUKONG LIMITED (KR) | 1998-10-06 | — | — | US | disclosed |