Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGIR | P43119 | 14/20 | 0.40 |
| ▸ | PTGDR | Q13258 | 5/20 | 0.36 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.36 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 5/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7778597 | 1.00 | PTGIR (0.40) | PTGIRPTGDRPTGER1PTGER3ACHE | |
| SCHEMBL7778522 | 1.00 | PTGIR (0.40) | PTGIRPTGDRPTGER1PTGER3ACHE | |
| SCHEMBL8486810 | 0.89 | PTGIR (0.40) | PTGIRPTGDRPTGER1PTGER3ACHE | |
| SCHEMBL7779678 | 0.84 | PTGIR (0.39) | PTGIRPTGDRPTGER1PTGER3ACHE | |
| SCHEMBL7776674 | 0.83 | PTGIR (0.42) | PTGIRPTGDRPTGER1PTGER3ACHE | |
| SCHEMBL7772415 | 0.83 | PTGIR (0.42) | PTGIRPTGDRPTGER1PTGER3ACHE | |
| SCHEMBL7772412 | 0.83 | PTGIR (0.42) | PTGIRPTGDRPTGER1PTGER3ACHE | |
| SCHEMBL7776663 | 0.83 | HTR1A (0.33) | ACHE | |
| SCHEMBL7776660 | 0.83 | HTR1A (0.33) | ACHE | |
| SCHEMBL7779788 | 0.83 | PTGIR (0.45) | PTGIRPTGDRPTGER1PTGER3CHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0749424-B1 | NAPHTHALENE DERIVATIVES AS PROSTAGLANDIN I2 AGONISTS | FUJISAWA PHARMACEUTICAL CO (JP) | 2001-09-12 | — | — | EP | disclosed |
| US-5763489-A | ANTICOAGULANTS AND HYPOTENSIVE AGENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-06-09 | — | — | US | disclosed |
| WO-1995024393-A1 | NAPHTHALENE DERIVATIVES AS PROSTAGLANDIN I2 AGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-09-14 | — | — | WO | disclosed |