Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGIR | P43119 | 20/20 | 0.64 |
| ▸ | PTGDR | Q13258 | 10/20 | 0.52 |
| ▸ | PTGER3 | P43115 | 3/20 | 0.52 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.52 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.45 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7778604 | 1.00 | PTGIR (0.64) | PTGIRPTGDRPTGER3PTGER1PTGER4 | |
| SCHEMBL7778607 | 1.00 | PTGIR (0.64) | PTGIRPTGDRPTGER3PTGER1PTGER4 | |
| SCHEMBL7717821 | 0.94 | PTGIR (0.60) | PTGIRPTGDRPTGER3PTGER1PTGER4 | |
| SCHEMBL7778570 | 0.89 | PTGIR (0.52) | PTGIRPTGDRPTGER3PTGER1PTGER4 | |
| SCHEMBL7778572 | 0.89 | PTGIR (0.52) | PTGIRPTGDRPTGER3PTGER1PTGER4 | |
| SCHEMBL9017276 | 0.89 | PTGIR (0.52) | PTGIRPTGDRPTGER3PTGER1PTGER4 | |
| SCHEMBL7776680 | 0.89 | PTGIR (0.52) | PTGIRPTGDRPTGER3PTGER1PTGER4 | |
| SCHEMBL7776682 | 0.89 | PTGIR (0.52) | PTGIRPTGDRPTGER3PTGER1PTGER4 | |
| SCHEMBL7776677 | 0.89 | PTGIR (0.52) | PTGIRPTGDRPTGER3PTGER1PTGER4 | |
| SCHEMBL7716590 | 0.82 | PTGIR (0.77) | PTGIRPTGDRPTGER3PTGER1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0749424-B1 | NAPHTHALENE DERIVATIVES AS PROSTAGLANDIN I2 AGONISTS | FUJISAWA PHARMACEUTICAL CO (JP) | 2001-09-12 | — | — | EP | disclosed |