Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGIR | P43119 | 18/20 | 0.52 |
| ▸ | PTGDR | Q13258 | 8/20 | 0.42 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.42 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.38 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7778572 | 1.00 | PTGIR (0.52) | PTGIRPTGDRPTGER3PTGER1ALDH1A1 | |
| SCHEMBL7778570 | 1.00 | PTGIR (0.52) | PTGIRPTGDRPTGER3PTGER1ALDH1A1 | |
| SCHEMBL7776680 | 1.00 | PTGIR (0.52) | PTGIRPTGDRPTGER3PTGER1ALDH1A1 | |
| SCHEMBL7776682 | 1.00 | PTGIR (0.52) | PTGIRPTGDRPTGER3PTGER1ALDH1A1 | |
| SCHEMBL7776677 | 1.00 | PTGIR (0.52) | PTGIRPTGDRPTGER3PTGER1ALDH1A1 | |
| SCHEMBL8487891 | 0.91 | PTGIR (0.49) | PTGIRPTGDRPTGER3PTGER1ALDH1A1 | |
| SCHEMBL7778607 | 0.89 | PTGIR (0.64) | PTGIRPTGDRPTGER3PTGER1PTGER4 | |
| SCHEMBL7778660 | 0.89 | PTGIR (0.64) | PTGIRPTGDRPTGER3PTGER1PTGER4 | |
| SCHEMBL7778604 | 0.89 | PTGIR (0.64) | PTGIRPTGDRPTGER3PTGER1PTGER4 | |
| SCHEMBL7717821 | 0.84 | PTGIR (0.60) | PTGIRPTGDRPTGER3PTGER1PTGER4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0749424-A1 | NAPHTHALENE DERIVATIVES AS PROSTAGLANDIN I2 AGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-12-27 | — | — | EP | disclosed |