Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 2/20 | 0.57 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.57 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.57 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.56 |
| ▸ | DRD2 | P14416 | 12/20 | 0.54 |
| ▸ | DRD3 | P35462 | 8/20 | 0.54 |
| ▸ | DRD4 | P21917 | 6/20 | 0.54 |
| ▸ | CA1 | P00915 | 2/20 | 0.52 |
| ▸ | CA2 | P00918 | 2/20 | 0.52 |
| ▸ | ACHE | P22303 | 2/20 | 0.52 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.50 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.49 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7778683 | 1.00 | CHRM2 (0.57) | CHRM2CHRM1CHRM3CYP19A1DRD2 | |
| SCHEMBL7776659 | 0.85 | CHRM2 (0.58) | CHRM2CHRM1CHRM3CYP19A1DRD2 | |
| SCHEMBL10827763 | 0.82 | CYP19A1 (0.44) | CYP19A1CA1CA2SIGMAR1MTNR1A | |
| SCHEMBL10043010 | 0.80 | DRD2 (0.57) | CHRM2CHRM1CHRM3CYP19A1DRD2 | |
| SCHEMBL3318329 | 0.80 | DRD2 (0.57) | CHRM2CHRM1CHRM3CYP19A1DRD2 | |
| SCHEMBL7777377 | 0.78 | CYP19A1 (0.64) | CHRM2CHRM1CHRM3CYP19A1DRD2 | |
| SCHEMBL9365199 | 0.78 | DRD2 (0.66) | CHRM2CHRM1CHRM3CYP19A1DRD2 | |
| SCHEMBL8414318 | 0.77 | CHRM2 (0.67) | CHRM2CHRM1CHRM3CYP19A1DRD2 | |
| Hydrochloric Acid SCHEMBL9688990 | 0.77 | DRD2 (0.64) | CHRM2CHRM1CHRM3CYP19A1DRD2 | |
| SCHEMBL29062558 | 0.77 | CYP19A1 (0.62) | CHRM2CHRM1CHRM3CYP19A1DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0749424-B1 | NAPHTHALENE DERIVATIVES AS PROSTAGLANDIN I2 AGONISTS | FUJISAWA PHARMACEUTICAL CO (JP) | 2001-09-12 | — | — | EP | disclosed |
| US-5863918-A | HYPOTENSIVE AGENTS, ANTICOAGULANTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1999-01-26 | — | — | US | disclosed |
| US-5763489-A | ANTICOAGULANTS AND HYPOTENSIVE AGENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-06-09 | — | — | US | disclosed |
| WO-1995024393-A1 | NAPHTHALENE DERIVATIVES AS PROSTAGLANDIN I2 AGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-09-14 | — | — | WO | disclosed |