Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLD1 | Q13393 | 1/20 | 0.51 |
| ▸ | CCR3 | P51677 | 1/20 | 0.48 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.47 |
| ▸ | HTR1A | P08908 | 4/20 | 0.46 |
| ▸ | HTR2C | P28335 | 1/20 | 0.46 |
| ▸ | DRD3 | P35462 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7817813 | 0.92 | HTR2C (0.49) | PLD1HTR2AHTR1AHTR2CDRD3 | |
| SCHEMBL7811689 | 0.88 | DRD4 (0.51) | PLD1CCR3HTR1AKDM4EALDH1A1 | |
| SCHEMBL7774151 | 0.86 | HPGD (0.56) | SLC6A4DRD3HPGD | |
| SCHEMBL7811687 | 0.86 | CCR2 (0.46) | PLD1CCR3HTR1ACYP1A2HPGD | |
| SCHEMBL8989699 | 0.83 | PLD1 (0.56) | PLD1CCR3HTR1AHTR2CDRD3 | |
| SCHEMBL8882719 | 0.82 | HPGD (0.52) | PLD1SLC6A4HTR1ADRD3CYP1A2 | |
| SCHEMBL7781108 | 0.82 | PLD1 (0.53) | PLD1CCR3HTR1ACD274 | |
| SCHEMBL7774077 | 0.81 | PLD1 (0.53) | PLD1CCR3HTR1AALDH1A1CD274 | |
| SCHEMBL7781808 | 0.81 | HTR2C (0.43) | PLD1HTR2AHTR1AHTR2CDRD3 | |
| SCHEMBL8576249 | 0.80 | F10 (0.39) | DRD3HPGDMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1133293-A1 | USE OF N-SUBSTITUTED AZABICYCLOALKANE DERIVATIVES FOR TREATING DISEASES OF THE CENTRAL NERVOUS SYSTEM | BASF AKTIENGESELLSCHAFT (DE) | 2001-09-19 | — | — | EP | disclosed |
| EP-0775113-B1 | N-SUBSTITUTED AZABICYCLOHEPTANE DERIVATIVES USEFUL AS NEUROLEPTICS | BASF AG (DE) | 2001-04-11 | — | — | EP | disclosed |
| WO-2000030639-A1 | USE OF N-SUBSTITUTED AZABICYCLOALKANE DERIVATIVES FOR TREATING DISEASES OF THE CENTRAL NERVOUS SYSTEM | BASF AKTIENGESELLSCHAFT (DE) | 2000-06-02 | — | — | WO | disclosed |