Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.39 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.39 |
| ▸ | AR | P10275 | 3/20 | 0.37 |
| ▸ | PGR | P06401 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL224653 | 0.80 | CYP1A2 (0.57) | CYP1A2CYP3A4CYP2C9CYP2C19TSHR | |
| SCHEMBL100732 | 0.80 | CYP1A2 (0.76) | CYP1A2CYP3A4CYP2C9CYP2C19TSHR | |
| SCHEMBL30320250 | 0.80 | CYP1A2 (0.57) | CYP1A2CYP3A4CYP2C9CYP2C19TSHR | |
| SCHEMBL514629 | 0.76 | CYP1A2 (0.53) | CYP1A2CYP3A4CYP2C9CYP2C19TSHR | |
| SCHEMBL4968573 | 0.76 | CYP1A2 (0.53) | CYP1A2CYP3A4CYP2C9CYP2C19TSHR | |
| SCHEMBL11213795 | 0.76 | CYP1A2 (0.53) | CYP1A2CYP3A4CYP2C9CYP2C19TSHR | |
| SCHEMBL2548458 | 0.76 | CYP1A2 (0.53) | CYP1A2CYP3A4CYP2C9CYP2C19TSHR | |
| SCHEMBL11241316 | 0.76 | CYP1A2 (0.53) | CYP1A2CYP3A4CYP2C9CYP2C19TSHR | |
| SCHEMBL1888696 | 0.76 | CYP1A2 (0.53) | CYP1A2CYP3A4CYP2C9CYP2C19TSHR | |
| SCHEMBL514630 | 0.76 | CYP1A2 (0.53) | CYP1A2CYP3A4CYP2C9CYP2C19TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0741129-B1 | Cyanobenzenesulfenyl halide and process for preparation of 3-substituted benzisothiazole using it | SUMITOMO SEIKA CHEMICALS (JP) | 1999-06-09 | — | — | EP | claimed |
| US-5679827-A | Cyanobenzenesulfenyl halide and process for preparation of 3-substituted benzisothiazole using the same | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 1997-10-21 | — | — | US | claimed |
| EP-0741129-A2 | Cyanobenzenesulfenyl halide and process for preparation of 3-substituted benzisothiazole using it | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 1996-11-06 | — | — | EP | claimed |
| EP-0835866-B1 | Process for preparation of 3-piperazinylbenzisothiazoles | SUMITOMO SEIKA CHEMICALS (JP) | 2001-08-16 | — | — | EP | disclosed |
| US-5939548-A | Process for preparation of 3-piperazinylbenzisothiazoles | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 1999-08-17 | — | — | US | disclosed |
| EP-0741129-B1 | Cyanobenzenesulfenyl halide and process for preparation of 3-substituted benzisothiazole using it | SUMITOMO SEIKA CHEMICALS (JP) | 1999-06-09 | — | — | EP | disclosed |
| US-5861511-A | Process for preparation of 3 piperazinylbenzisothiazoles | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 1999-01-19 | — | — | US | disclosed |
| US-5756806-A | Cyanobenzenesulfenyl halide and process for preparation of 3-substituted benzisothiazole using the same | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 1998-05-26 | — | — | US | disclosed |
| EP-0835866-A1 | Process for preparation of 3-piperazinylbenzisothiazoles | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 1998-04-15 | — | — | EP | disclosed |
| US-5679827-A | Cyanobenzenesulfenyl halide and process for preparation of 3-substituted benzisothiazole using the same | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 1997-10-21 | — | — | US | disclosed |
| EP-0741129-A2 | Cyanobenzenesulfenyl halide and process for preparation of 3-substituted benzisothiazole using it | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 1996-11-06 | — | — | EP | disclosed |