Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB5 | P28074 | 7/20 | 0.34 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.34 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
| ▸ | TYMP | P19971 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 3/20 | 0.32 |
| ▸ | DRD4 | P21917 | 3/20 | 0.32 |
| ▸ | DRD3 | P35462 | 3/20 | 0.32 |
| ▸ | JAK2 | O60674 | 1/20 | 0.30 |
| ▸ | JAK1 | P23458 | 1/20 | 0.30 |
| ▸ | JAK3 | P52333 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2745183 | 0.95 | PDGFRB (0.32) | TYMPDRD2DRD4DRD3 | |
| SCHEMBL8733938 | 0.74 | TDP1 (0.37) | PSMB5ELANETDP1DRD2DRD4 | |
| SCHEMBL2744962 | 0.73 | JAK2 (0.37) | PSMB5PSMB1ELANETDP1JAK2 | |
| SCHEMBL13197036 | 0.72 | PSMB5 (0.50) | PSMB5PSMB1DRD2DRD4DRD3 | |
| SCHEMBL2744580 | 0.67 | PTGER1 (0.33) | PSMB5PSMB1TDP1JAK2JAK1 | |
| SCHEMBL2744834 | 0.66 | PSMB5 (0.40) | PSMB5PSMB1TYMPTDP1 | |
| SCHEMBL9835819 | 0.65 | PDE3B (0.52) | PSMB5PSMB1ELANETYMPDRD2 | |
| SCHEMBL9737184 | 0.64 | MAPK13 (0.51) | — | |
| SCHEMBL8576194 | 0.61 | METAP2 (0.48) | TDP1 | |
| SCHEMBL296554 | 0.61 | TYMP (0.42) | PSMB5PSMB1ELANETYMPTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0885251-B1 | SUBSTITUTED POLYTHIOPHENES, PROCESSES FOR THEIR PREPARATION AND THEIR USE | BASF AG (DE) | 2001-08-16 | — | — | EP | disclosed |