Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL710533 | 0.90 | MAPK1 (0.36) | NPC1RAB9APOLBLMNAMEN1 | |
| SCHEMBL29706521 | 0.90 | MAPK1 (0.36) | NPC1RAB9APOLBLMNAMEN1 | |
| SCHEMBL29350743 | 0.87 | NPC1 (0.45) | NPC1RAB9APOLBLMNAMEN1 | |
| SCHEMBL39146 | 0.87 | NPC1 (0.45) | NPC1RAB9APOLBLMNAMEN1 | |
| SCHEMBL382056 | 0.87 | NPC1 (0.38) | NPC1RAB9APOLB | |
| SCHEMBL5834134 | 0.87 | NPC1 (0.35) | NPC1RAB9APOLB | |
| SCHEMBL29567315 | 0.87 | NPC1 (0.38) | NPC1RAB9APOLB | |
| SCHEMBL5834387 | 0.87 | NPC1 (0.35) | NPC1RAB9APOLBMEN1KMT2A | |
| SCHEMBL586578 | 0.86 | NPC1 (0.44) | NPC1RAB9APOLBLMNAMEN1 | |
| SCHEMBL11457333 | 0.86 | NPC1 (0.44) | NPC1RAB9APOLBLMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1144391-A1 | ONE-POT PROCESS FOR THE PREPARATION OF 5-SULFONYL-SUBSTITUTED BENZOTRIAZOLES | Ciba SC Holding AG (CH) | 2001-10-17 | — | — | EP | disclosed |
| WO-2000043376-A1 | ONE-POT PROCESS FOR THE PREPARATION OF 5-SULFONYL-SUBSTITUTED BENZOTRIAZOLES | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2000-07-27 | — | — | WO | disclosed |
| US-6040455-A | REACTING A HALOBENZOTRIAZOLE COMPOUND WITH ALIPHATIC, PHENYLALKYL OR ARYL MERCAPTAN COMPOUND TO FORM 5-THIO SUBSTITUTED BENZOTRIAZOLE, OXIDIZING WITH HYDROGEN PEROXIDE TO FOR 5-SULFONE SUBSTITUED BENZOTRIAZOLE COMPOUND | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2000-03-21 | — | — | US | disclosed |