Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 3/20 | 0.42 |
| ▸ | METAP1 | P53582 | 3/20 | 0.42 |
| ▸ | GPR88 | Q9GZN0 | 8/20 | 0.36 |
| ▸ | TLR2 | O60603 | 1/20 | 0.36 |
| ▸ | CTSC | P53634 | 2/20 | 0.35 |
| ▸ | DPP4 | P27487 | 1/20 | 0.34 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7779006 | 0.99 | METAP2 (0.42) | METAP2METAP1GPR88TLR2CTSC | |
| Hydrochloric Acid SCHEMBL7779012 | 0.99 | METAP2 (0.42) | METAP2METAP1GPR88TLR2CTSC | |
| SCHEMBL6559219 | 0.88 | METAP2 (0.47) | METAP2METAP1GPR88CTSCDPP4 | |
| SCHEMBL6559201 | 0.88 | METAP2 (0.47) | METAP2METAP1GPR88CTSCDPP4 | |
| Hydrochloric Acid SCHEMBL6560458 | 0.87 | METAP2 (0.46) | METAP2METAP1GPR88CTSCDPP4 | |
| Hydrochloric Acid SCHEMBL6560449 | 0.87 | METAP2 (0.46) | METAP2METAP1GPR88CTSCDPP4 | |
| SCHEMBL7784058 | 0.86 | METAP2 (0.47) | METAP2METAP1GPR88EPHX2 | |
| Hydrochloric Acid SCHEMBL7784059 | 0.85 | METAP2 (0.46) | METAP2METAP1GPR88 | |
| Hydrochloric Acid SCHEMBL7784056 | 0.85 | METAP2 (0.46) | METAP2METAP1GPR88 | |
| Hydrochloric Acid SCHEMBL6560650 | 0.81 | METAP2 (0.45) | METAP2METAP1GPR88SCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140979-A1 | POLYOL COMPOUNDS, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000040599-A1 | POLYOL COMPOUNDS, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2000-07-13 | — | — | WO | disclosed |