SCHEMBL7779018

SCHEMBL7779018

[O-][S+](Cc1ccc(Br)cc1)Cc1ccc(Br)cc1

nearest known ligand 0.46

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 3/20 0.42
HTR2A P28223 1/20 0.42
CYP2A6 P11509 1/20 0.42
IDO1 P14902 4/20 0.41
HRH3 Q9Y5N1 1/20 0.36
PLCG1 P19174 1/20 0.36
PYCR1 P32322 2/20 0.34
ALOX15 P16050 2/20 0.33
AGER Q15109 1/20 0.33
ALDH1A1 P00352 1/20 0.33
MAPK1 P28482 1/20 0.33
APP P05067 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20246275 0.80 TAAR1 (0.39) TAAR1HTR2ACYP2A6IDO1PLCG1
SCHEMBL14204493 0.80 TAAR1 (0.40) TAAR1HTR2ACYP2A6IDO1PLCG1
SCHEMBL3230192 0.77 CNR1 (0.40) TAAR1HTR2A
SCHEMBL29051238 0.75 TAAR1 (0.50) TAAR1HTR2ACYP2A6IDO1PLCG1
SCHEMBL8005325 0.74 HTT (0.48) ALDH1A1MAPK1
SCHEMBL777796 0.74 IDO1 (0.46) TAAR1IDO1
SCHEMBL196856 0.74 IDO1 (0.46) TAAR1HTR2ACYP2A6IDO1ALDH1A1
SCHEMBL4401171 0.74 IDO1 (0.46) TAAR1CYP2A6IDO1HRH3ALDH1A1
SCHEMBL61714 0.74 ESR1 (0.50) TAAR1IDO1ALOX15ALDH1A1
SCHEMBL3841233 0.74 CYP3A4 (0.50) HRH3ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117778339-A Sulfoxide reductase mutant and application thereof in preparation of chiral sulfoxide and sulfinyl ester 遵义医科大学 2024-03-29 CN disclosed
CN-117757763-A Sulfoxide reductase mutant and application thereof in chiral sulfoxide preparation 遵义医科大学 2024-03-26 CN disclosed
CN-106045804-B A method of based on temperature sensitive type ionic liquid chirality Salen Ti composition catalyst aqueous catalysis thioether asymmetric oxidation reaction 湖南师范大学 2019-01-11 CN disclosed
CN-105879914-B A kind of temperature sensitive type ionic liquid chirality Salen Ti composition catalysts and preparation method thereof 湖南师范大学 2018-03-30 CN disclosed
CN-106045804-A Method for realizing asymmetric oxidation reaction of thioether under aqueous-phase catalysis of chiral Salen Ti complex catalyst based on temperature-sensitive type ionic liquid 湖南师范大学 2016-10-26 CN disclosed
CN-105879914-A Temperature-sensitive type ionic liquid chiral Salen Ti complex catalyst and preparation method thereof 湖南师范大学 2016-08-24 CN disclosed
EP-0870304-B1 SEMICONDUCTING POLYMER KONINKL PHILIPS ELECTRONICS NV (NL) 2001-09-12 EP disclosed
US-5908583-A Semiconductor polymer U.S. PHILIPS CORPORATION (US) 1999-06-01 US disclosed
EP-0870304-A1 SEMICONDUCTING POLYMER Koninklijke Philips Electronics N.V. (NL) 1998-10-14 EP disclosed
WO-1998001868-A1 SEMICONDUCTING POLYMER PHILIPS ELECTRONICS N.V. (NL) 1998-01-15 WO disclosed