Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.33 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.33 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | PPM1B | O75688 | 1/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
| ▸ | PPP1CC | P36873 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7785980 | 0.77 | GAA (0.38) | GAATP53SMN1; SMN2ALDH1A1CHRNB2 | |
| SCHEMBL16552322 | 0.77 | GAA (0.42) | GAATP53SMN1; SMN2ALDH1A1CHRNB2 | |
| SCHEMBL2948892 | 0.74 | TP53 (0.56) | GAATP53SMN1; SMN2ALDH1A1CHRNB2 | |
| SCHEMBL244740 | 0.74 | — | — | |
| SCHEMBL2200767 | 0.74 | TP53 (0.56) | GAATP53SMN1; SMN2ALDH1A1CHRNB2 | |
| SCHEMBL74396 | 0.74 | TP53 (0.56) | GAATP53SMN1; SMN2ALDH1A1CHRNB2 | |
| SCHEMBL18842337 | 0.74 | GAA (0.41) | GAATP53SMN1; SMN2ALDH1A1CHRNB2 | |
| SCHEMBL31067200 | 0.74 | GAA (0.41) | GAATP53SMN1; SMN2ALDH1A1CHRNB2 | |
| SCHEMBL17803033 | 0.74 | TP53 (0.44) | GAATP53SMN1; SMN2ALDH1A1CHRNB2 | |
| SCHEMBL1467609 | 0.74 | TP53 (0.44) | GAATP53SMN1; SMN2ALDH1A1CHRNB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140787-A1 | CROSSLINKERS BASED ON DIBENZALACETONE DERIVATIVES | Eastman Chemical Company (US) | 2001-10-10 | — | — | EP | claimed |
| WO-2000035854-A1 | CROSSLINKERS BASED ON DIBENZALACETONE DERIVATIVES | EASTMAN CHEMICAL COMPANY (US) | 2000-06-22 | — | — | WO | claimed |
| EP-1140787-A1 | CROSSLINKERS BASED ON DIBENZALACETONE DERIVATIVES | Eastman Chemical Company (US) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000035854-A1 | CROSSLINKERS BASED ON DIBENZALACETONE DERIVATIVES | EASTMAN CHEMICAL COMPANY (US) | 2000-06-22 | — | — | WO | disclosed |