SCHEMBL7779298

SCHEMBL7779298

COC(=O)c1c(C(=O)O)c(C(=O)O)c2cc(C)ccc2c1C(=O)O

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LDHA P00338 3/20 0.53
LDHB P07195 3/20 0.53
ALB P02768 1/20 0.49
KMT2A Q03164 3/20 0.48
MEN1 O00255 1/20 0.48
NR4A2 P43354 2/20 0.45
TDP1 Q9NUW8 2/20 0.43
KDM4E B2RXH2 5/20 0.41
ALDH1A1 P00352 4/20 0.41
HSD17B10 Q99714 2/20 0.41
HPGD P15428 2/20 0.41
GLA P06280 1/20 0.40
TSHR P16473 1/20 0.40
MAPT P10636 3/20 0.40
GAA P10253 1/20 0.40
POLB P06746 2/20 0.40
MITF O75030 1/20 0.39
MAPK8 P45983 1/20 0.39
CA12 O43570 1/20 0.39
CA1 P00915 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28032836 0.77 MEN1 (0.63) KMT2AMEN1NR4A2TDP1KDM4E
SCHEMBL25837400 0.75 LDHA (0.69) LDHALDHBALBKMT2ANR4A2
SCHEMBL27768938 0.75 CA12 (0.48) KMT2AMEN1TDP1KDM4EALDH1A1
SCHEMBL31149860 0.75 CA12 (0.48) KMT2AMEN1TDP1KDM4EALDH1A1
SCHEMBL11415957 0.75 CA12 (0.48) KMT2AMEN1TDP1KDM4EALDH1A1
SCHEMBL25381186 0.75 CA12 (0.48) KMT2AMEN1TDP1KDM4EALDH1A1
SCHEMBL25377022 0.75 CA12 (0.48) KMT2AMEN1TDP1KDM4EALDH1A1
SCHEMBL25380099 0.75 CA12 (0.48) KMT2AMEN1TDP1KDM4EALDH1A1
SCHEMBL28051326 0.75 CA12 (0.48) KMT2AMEN1TDP1KDM4EALDH1A1
SCHEMBL709081 0.73 NR4A2 (0.49) LDHALDHBALBKMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0879695-B1 Biaxially oriented laminate film of wholly aromatic polyamide and magnetic recording media TEIJIN LTD (JP) 2001-10-24 EP disclosed
US-6124021-A FILM OF AN AROMATIC POLYAMIDE LAYER A AND AN AROMATIC POLYAMIDE LAYER B CONTAINING AN INERT FINE PARTICLES LAMINATED ON ONE SURFACE OF LAYER A, THE OTHER SURFACE OF B IS ROUGHER THAN A; OTHER SURFACE OF A HAS PROJECTIONS TEIJIN LIMITED (JP) 2000-09-26 US disclosed
EP-0879695-A2 Biaxially oriented laminate film of wholly aromatic polyamide and magnetic recording media TEIJIN LIMITED (JP) 1998-11-25 EP disclosed