SCHEMBL7779312

SCHEMBL7779312

CCCCCC1COC(CCC2COC(CCCCC)OC2)OC1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.54
EPHX1 P07099 1/20 0.41
PRKD3 O94806 2/20 0.40
PRKCG P05129 2/20 0.40
PRKCB P05771 2/20 0.40
PRKCA P17252 2/20 0.40
PRKCH P24723 2/20 0.40
PRKCI P41743 2/20 0.40
PRKCE Q02156 2/20 0.40
PRKCQ Q04759 2/20 0.40
PRKCZ Q05513 2/20 0.40
PRKCD Q05655 2/20 0.40
PRKD1 Q15139 2/20 0.40
ENPP2 Q13822 5/20 0.38
LPAR2 Q9HBW0 4/20 0.38
CYP1A2 P05177 2/20 0.38
TDP1 Q9NUW8 1/20 0.37
SPHK1 Q9NYA1 4/20 0.37
SPHK2 Q9NRA0 3/20 0.37
SMN1; SMN2 Q16637 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7779306 1.00 ALDH1A1 (0.54) ALDH1A1EPHX1PRKD3PRKCGPRKCB
SCHEMBL9617852 0.96 ALDH1A1 (0.58) ALDH1A1EPHX1PRKD3PRKCGPRKCB
SCHEMBL7778929 0.94 ALDH1A1 (0.47) ALDH1A1EPHX1PRKD3PRKCGPRKCB
SCHEMBL7778933 0.94 ALDH1A1 (0.47) ALDH1A1EPHX1PRKD3PRKCGPRKCB
SCHEMBL24562883 0.94 ALDH1A1 (0.61) ALDH1A1EPHX1PRKD3PRKCGPRKCB
SCHEMBL7781485 0.94 ALDH1A1 (0.56) ALDH1A1EPHX1PRKD3PRKCGPRKCB
SCHEMBL7781481 0.94 ALDH1A1 (0.56) ALDH1A1EPHX1PRKD3PRKCGPRKCB
SCHEMBL7779384 0.92 ALDH1A1 (0.50) ALDH1A1EPHX1PRKD3PRKCGPRKCB
SCHEMBL7781520 0.92 ALDH1A1 (0.45) ALDH1A1EPHX1PRKD3PRKCGPRKCB
SCHEMBL7781518 0.92 ALDH1A1 (0.45) ALDH1A1EPHX1PRKD3PRKCGPRKCB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0732330-B1 Di-1,3-dioxane derivatives useful as liquid crystals ROLIC AG (CH) 2001-09-12 EP disclosed
US-5667721-A Liquid crystalline di-1,3-dioxane derivatives ROLIC AG (CH) 1997-09-16 US disclosed
EP-0732330-A1 Di-1,3-dioxane derivatives useful as liquid crystals F. HOFFMANN-LA ROCHE AG (CH) 1996-09-18 EP disclosed