Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | MC4R | P32245 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7779659 | 1.00 | KMT2A (0.48) | KMT2AALDH1A1MC4RMEN1SIGMAR1 | |
| SCHEMBL7786460 | 1.00 | KMT2A (0.48) | KMT2AALDH1A1MC4RMEN1SIGMAR1 | |
| Hydrochloric Acid SCHEMBL8477512 | 0.99 | KMT2A (0.47) | KMT2AALDH1A1MC4RMEN1SIGMAR1 | |
| SCHEMBL7787742 | 0.93 | MC4R (0.52) | KMT2AALDH1A1MC4RSIGMAR1TAAR1 | |
| SCHEMBL7787741 | 0.93 | MC4R (0.52) | KMT2AALDH1A1MC4RSIGMAR1TAAR1 | |
| Hydrochloric Acid SCHEMBL7787634 | 0.92 | MC4R (0.51) | KMT2AALDH1A1MC4RMEN1SIGMAR1 | |
| Hydrochloric Acid SCHEMBL7787633 | 0.92 | MC4R (0.51) | KMT2AALDH1A1MC4RMEN1SIGMAR1 | |
| SCHEMBL8477270 | 0.86 | MC4R (0.55) | KMT2AALDH1A1MC4RMEN1SIGMAR1 | |
| SCHEMBL7784237 | 0.86 | MC4R (0.55) | KMT2AALDH1A1MC4RMEN1SIGMAR1 | |
| Hydrochloric Acid SCHEMBL7786422 | 0.85 | MC4R (0.53) | KMT2AALDH1A1MC4RMEN1SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0837679-B1 | 2-(1H-4(5)-IMIDAZOYL) CYCLOPROPYL DERIVATIVES | GLIATECH INC (US) | 2001-10-24 | — | — | EP | disclosed |
| US-6008240-A | AN ANTAGONIST OF HISTAMINE H3 RECEPTORS; FOR TREATING ALLERGY, INFLAMMATION, CARDIOVASCULAR DISEASE (HYPER OR HYPOTENSION), GASTROINTESTINAL DISORDERS, CNS DISORDERS INVOLVING ATTENTION OR COGNITIVE DISORDERS | GLIATECH, INC. (US) | 1999-12-28 | — | — | US | disclosed |