SCHEMBL7780077

SCHEMBL7780077

NCC(=O)OC(=O)C[C@H](N)C(=O)O

nearest known ligand 0.43

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
GRIK1 P39086 6/20 0.43
GRIK2 Q13002 3/20 0.43
GRM1 Q13255 1/20 0.43
GRM2 Q14416 1/20 0.43
GRIA4 P48058 3/20 0.42
GRIK3 Q13003 3/20 0.42
GRIK5 Q16478 3/20 0.42
SLC7A5 Q01650 1/20 0.41
PTGS1 P23219 1/20 0.39
SLC7A11 Q9UPY5 1/20 0.39
GGT1 P19440 4/20 0.39
SLC1A1 P43005 4/20 0.39
GSR P00390 1/20 0.39
SLC1A3 P43003 2/20 0.38
SLC1A2 P43004 2/20 0.38
GRIA2 P42262 2/20 0.37
GRIA1 P42261 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL307010 0.83
SCHEMBL9701317 0.83 GRIK1 (0.45) GRIK1GRIK2GRM1GRM2GRIA4
Serine SCHEMBL1064689 0.83 SLC1A1 (0.43) GRIK1GRIK2GRM1GRM2GRIA4
SCHEMBL17222477 0.83 GRIK1 (0.45) GRIK1GRIK2GRM1GRM2GRIA4
SCHEMBL27399004 0.82 GRIK1 (0.46) GRIK1GRIK2GRM1GRM2GRIA4
SCHEMBL28048940 0.82 GRIK1 (0.46) GRIK1GRIK2GRM1GRM2GRIA4
Asparagine SCHEMBL7563049 0.81 SLC1A1 (0.40) GRIK1GRIK2GRM1GRM2GRIA4
SCHEMBL27578538 0.81
SCHEMBL27815508 0.80 GSR (0.47) GRIK1GRIK2GRM1GRM2GRIA4
SCHEMBL28204942 0.80 GRIK1 (0.45) GRIK1GRIK2GRM1GRM2GRIA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4384221-A1 CONTROLLED DRUG RELEASE MATERIAL Aduro Material Ab (SE) 2024-06-19 EP disclosed
WO-2023018366-A1 CONTROLLED DRUG RELEASE MATERIAL ADURO MATERIAL AB (SE) 2023-02-16 WO disclosed
EP-3102611-A1 HUMANIZED BETA-AMYLOID BINDING MOLECULES AND USES THEREOF Cangene Corporation (CA) 2016-12-14 EP disclosed
WO-2015113169-A1 HUMANIZED BETA-AMYLOID BINDING MOLECULES AND USES THEREOF CNJ HOLDINGS, INC. (CA) 2015-08-06 WO disclosed
CN-103966248-A Bacterium gene point mutation molecular cloning technology based on homologus recombination HANGZHOPU CT FOR DISEASE CONTROL AND PREVENTION 2014-08-06 CN disclosed
CN-101365807-A Polymerases for incorporation of nucleotide analogs PACIFIC BIOSCIENCES CALIFORNIA (US) 2009-02-11 CN disclosed
US-6303357-B1 HEAT STABLE ENZYMATIC POLYPEPTIDE; FOR USE AS A DIAGNOSTIC TOOL IN MEASUREMENT OF LIPASE ACTIVITY AND DETERMINATION OF TRIGLYCERIDE, GLYCEROL, ADENOSINE TRIPHOSPHATE CONCENTRATIONS AMANO PHARMACEUTICAL CO., LTD. (JP) 2001-10-16 US disclosed
EP-1138769-A1 Recombinant L-alpha-glycerophosphate oxidase gene, and method for producing the same AMANO PHARMACEUTICAL CO., LTD. (JP) 2001-10-04 EP disclosed
CN-1069346-C Expression and secretion of hereologous proteins by yarrowia lipolytica transformants PFIZER (US) 2001-08-08 CN disclosed
CN-1034428-C Expression and Secretion of Heterologous Proteins Using Yarrowia lipolytica Transformants PFIZER (US) 1997-04-02 CN disclosed
CN-1141339-A Expression and secretion of hereologous proteins by yarrowia lipolytica transformants PFIZER (US) 1997-01-29 CN disclosed
CN-1138632-A Expression and secretion of hereologous proteins by yarrowia lipolytica transformants PFIZER (US) 1996-12-25 CN disclosed
EP-0400010-A1 SOLUBLE HUMAN CD4 FRAGMENTS AND USES THEREFOR DANA-FARBER CANCER INSTITUTE (US) 1990-12-05 EP disclosed
US-4921940-A Process for the purification of Ti containing polycarbonate with solvent, complexing agent and water XEROX CORPORATION (US) 1990-05-01 US disclosed
WO-1989003222-A1 SOLUBLE HUMAN CD4 FRAGMENTS AND USES THEREFOR DANA-FABER CANCER INSTITUTE (US) 1989-04-20 WO disclosed