SCHEMBL28048940

SCHEMBL28048940

CC(=O)CC(=O)OC(=O)C[C@H](N)C(=O)O

nearest known ligand 0.46

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
GRIK1 P39086 11/20 0.46
GRIA4 P48058 3/20 0.43
GRIK3 Q13003 3/20 0.43
GRIK5 Q16478 3/20 0.43
SLC1A1 P43005 4/20 0.42
SLC7A5 Q01650 2/20 0.42
MGAM O43451 1/20 0.41
GAA P10253 1/20 0.41
SI P14410 1/20 0.41
MGAM2 Q2M2H8 1/20 0.41
GRIK2 Q13002 6/20 0.41
GRM1 Q13255 1/20 0.39
GRM2 Q14416 1/20 0.39
SLC1A3 P43003 4/20 0.38
SLC1A2 P43004 4/20 0.38
GRIA2 P42262 2/20 0.38
GRIA1 P42261 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7781249 0.82 GRIK1 (0.50) GRIK1GRIA4GRIK3GRIK5SLC1A1
SCHEMBL7780077 0.82 GRIK1 (0.43) GRIK1GRIA4GRIK3GRIK5SLC1A1
SCHEMBL28518053 0.81 SLC1A1 (0.48) GRIK1GRIA4GRIK3GRIK5SLC1A1
SCHEMBL27723805 0.81 GRIK1 (0.44) GRIK1GRIA4GRIK3GRIK5SLC1A1
Acetic Acid SCHEMBL27618718 0.80 GRIK1 (0.48) GRIK1GRIA4GRIK3GRIK5SLC1A1
SCHEMBL8557428 0.78 GRIK1 (0.50) GRIK1GRIA4GRIK3GRIK5SLC1A1
SCHEMBL28219168 0.78 SMN1; SMN2 (0.43) MGAMGAASIMGAM2
SCHEMBL9701317 0.78 GRIK1 (0.45) GRIK1GRIA4GRIK3GRIK5SLC1A1
SCHEMBL17222477 0.78 GRIK1 (0.45) GRIK1GRIA4GRIK3GRIK5SLC1A1
SCHEMBL151676 0.77 SLC1A1 (0.58) GRIK1GRIA4GRIK3GRIK5SLC1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105344709-B A method of repairing harmful organic substance and/or heavy metal pollution matrix 迈科珍生物技术有限公司 2019-05-14 CN disclosed
CN-105344709-A A method for the remediation of harmful organics and/or heavy metal contaminated matrix MICROGEN BIOTECH LTD 2016-02-24 CN disclosed