Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM5 | P08912 | 1/20 | 0.73 |
| ▸ | CHKA | P35790 | 1/20 | 0.73 |
| ▸ | MAPT | P10636 | 6/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.50 |
| ▸ | RAB9A | P51151 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | CASP1 | P29466 | 1/20 | 0.50 |
| ▸ | HBB | P68871 | 1/20 | 0.50 |
| ▸ | GFER | P55789 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | MPO | P05164 | 1/20 | 0.45 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL9762926 | 0.93 | CHRM5 (0.76) | CHRM5CHKAMAPTSMN1; SMN2ALDH1A1 | |
| Acetone SCHEMBL28700630 | 0.93 | CHRM5 (0.76) | CHRM5CHKAMAPTSMN1; SMN2ALDH1A1 | |
| Bicarbonate SCHEMBL28588179 | 0.91 | CHRM5 (0.73) | CHRM5CHKAMAPTSMN1; SMN2ALDH1A1 | |
| Bicarbonate SCHEMBL28267252 | 0.91 | CHRM5 (0.73) | CHRM5CHKAMAPTSMN1; SMN2ALDH1A1 | |
| Bicarbonate SCHEMBL28588177 | 0.87 | CHRM5 (0.67) | CHRM5CHKAMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL28166029 | 0.86 | CHRM5 (0.73) | CHRM5CHKAMAPTSMN1; SMN2ALDH1A1 | |
| Benzene SCHEMBL28113160 | 0.85 | CHRM5 (0.89) | CHRM5CHKAMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL1845474 | 0.85 | CHRM5 (0.64) | CHRM5CHKAMAPTSMN1; SMN2ALDH1A1 | |
| Propionic Acid SCHEMBL28433613 | 0.85 | CHRM5 (0.64) | CHRM5CHKAMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL189 | 0.85 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4323425-A1 | POLYPROPIOLACTONES AND METHODS OF PREPARATION | Novomer, Inc. (US) | 2024-02-21 | — | — | EP | claimed |
| CN-117157342-A | Polypropylene lactone and preparation method | 诺沃梅尔公司 | 2023-12-01 | — | — | CN | claimed |
| WO-2022221266-A1 | POLYPROPIOLACTONES AND METHODS OF PREPARATION | NOVOMER, INC. (US) | 2022-10-20 | — | — | WO | claimed |
| US-20200290267-A1 | Three-Dimensional Printing of Impregnated Plastics for Chemical Reactions | UCL BUSINESS PLC (GB) | 2020-09-17 | — | — | US | claimed |
| CN-111100036-A | Preparation method and device of 1-cyano-2-propenyl acetate | 山东新和成氨基酸有限公司 | 2020-05-05 | — | — | CN | claimed |
| EP-3430473-A1 | THREE-DIMENSIONAL PRINTING OF IMPREGNATED PLASTICS FOR CHEMICAL REACTIONS | UCL Business Plc. (GB) | 2019-01-23 | — | — | EP | claimed |
| US-20260071024-A1 | POLYPROPIOLACTONES AND METHODS OF PREPARATION | NOVOMER INC (US) | 2026-03-12 | — | — | US | disclosed |
| US-12338318-B2 | Polypropiolactones and methods of preparation | NOVOMER, INC. (US) | 2025-06-24 | — | — | US | disclosed |
| US-20240228695-A1 | POLYPROPIOLACTONES AND METHODS OF PREPARATION | NOVOMER INC (US) | 2024-07-11 | — | — | US | disclosed |
| EP-4323425-A1 | POLYPROPIOLACTONES AND METHODS OF PREPARATION | Novomer, Inc. (US) | 2024-02-21 | — | — | EP | disclosed |
| CN-117157342-A | Polypropylene lactone and preparation method | 诺沃梅尔公司 | 2023-12-01 | — | — | CN | disclosed |
| WO-2022221266-A1 | POLYPROPIOLACTONES AND METHODS OF PREPARATION | NOVOMER, INC. (US) | 2022-10-20 | — | — | WO | disclosed |
| US-20200290267-A1 | Three-Dimensional Printing of Impregnated Plastics for Chemical Reactions | UCL BUSINESS PLC (GB) | 2020-09-17 | — | — | US | disclosed |
| EP-3430473-A1 | THREE-DIMENSIONAL PRINTING OF IMPREGNATED PLASTICS FOR CHEMICAL REACTIONS | UCL Business Plc. (GB) | 2019-01-23 | — | — | EP | disclosed |
| CN-109073966-A | The chemical reaction 3 D-printing of impregnated plastic | UCL商业有限公司 | 2018-12-21 | — | — | CN | disclosed |
| EP-0830341-B1 | PROCESSES FOR THE PREPARATION OF 3-(METHYLTHIO)PROPANAL AND 2-HYDROXY-4-(METHYLTHIO)BUTANENITRILE | NOVUS INT INC (US) | 2001-09-05 | — | — | EP | disclosed |
| EP-0830341-A1 | PROCESSES FOR THE PREPARATION OF 3-(METHYLTHIO)PROPANAL AND 2-HYDROXY-4-(METHYLTHIO)BUTANENITRILE | Novus International, Inc. (US) | 1998-03-25 | — | — | EP | disclosed |
| WO-1996040631-A1 | PROCESSES FOR THE PREPARATION OF 3-(METHYLTHIO)PROPANAL AND 2-HYDROXY-4-(METHYLTHIO)BUTANENITRILE | NOVUS INTERNATIONAL, INC. (US) | 1996-12-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260071024-A1 | POLYPROPIOLACTONES AND METHODS OF PREPARATION | NOTUM, ALKBH3, EBP | CHRM5 1897/4885CHKA 1894/4885MAPT 355/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.