Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPKAPK2 | P49137 | 11/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | AURKB | Q96GD4 | 3/20 | 0.34 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.34 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.34 |
| ▸ | CSNK1G1 | Q9HCP0 | 2/20 | 0.34 |
| ▸ | DCLK1 | O15075 | 1/20 | 0.34 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.34 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.34 |
| ▸ | GSK3A | P49840 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7780375 | 0.93 | KMT2A (0.42) | MAPKAPK2MEN1KMT2APOLBMAPK14 | |
| SCHEMBL7787611 | 0.91 | MAPKAPK2 (0.46) | MAPKAPK2MEN1KMT2APOLBMAPK14 | |
| SCHEMBL7780422 | 0.89 | MAPKAPK2 (0.41) | MAPKAPK2MAPK14MAPK1AURKBROCK1 | |
| SCHEMBL7780556 | 0.87 | ALDH1A1 (0.44) | MAPKAPK2MEN1KMT2APOLBTSHR | |
| SCHEMBL7780332 | 0.86 | MEN1 (0.48) | MAPKAPK2MEN1KMT2APOLBTSHR | |
| SCHEMBL7789059 | 0.85 | MAPKAPK2 (0.49) | MAPKAPK2MEN1KMT2AMAPK14GAA | |
| SCHEMBL7787545 | 0.85 | MAPKAPK2 (0.42) | MAPKAPK2MAPK14MAPK1AURKBROCK1 | |
| SCHEMBL7780525 | 0.85 | MAPKAPK2 (0.42) | MAPKAPK2MAPK14MAPK1AURKBROCK1 | |
| SCHEMBL7780311 | 0.85 | MEN1 (0.39) | MAPKAPK2MEN1KMT2APOLBMAPK14 | |
| SCHEMBL7787853 | 0.85 | KMT2A (0.38) | MAPKAPK2MEN1KMT2APOLBMAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6329405-B1 | AS ILEAL BILE ACID TRANSPORTER INHIBITOR, FOR THERAPY OF HYPERLIPEMIA | SANKYO COMPANY, LIMITED (JP) | 2001-12-11 | — | — | US | disclosed |
| EP-1070703-A1 | Cyclobutene derivatives | Sankyo Company Limited (JP) | 2001-01-24 | — | — | EP | disclosed |