SCHEMBL77807

SCHEMBL77807

CC(C(F)(F)F)C(F)(F)F

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.31
HSD17B10 Q99714 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25028393 0.90 ALDH1A1 (0.31) ALDH1A1HSD17B10
SCHEMBL799182 0.90 ALDH1A1 (0.31) ALDH1A1HSD17B10
SCHEMBL2294981 0.82
SCHEMBL12203191 0.82
SCHEMBL6930148 0.82
SCHEMBL15034674 0.79
SCHEMBL9168338 0.79
SCHEMBL20779032 0.79
SCHEMBL20013825 0.79
SCHEMBL19256991 0.79

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 777 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11779911-B2 Production of fatty olefin derivatives via olefin metathesis PROVIVI, INC. (US) 2023-10-10 US claimed
CN-113789156-B Heat transfer composition and application thereof and heat transfer system 浙江巨化联州制冷科技有限公司 2023-07-25 CN claimed
US-20220032280-A1 PRODUCTION OF FATTY OLEFIN DERIVATIVES VIA OLEFIN METATHESIS PROVIVI, INC. (US) 2022-02-03 US claimed
EP-3468964-B1 MODULATORS OF SOCE, COMPOSITIONS, AND USES THEREOF UNIV DEGLI STUDI DEL PIEMONTE ORIENTALE AMEDEO AVOGADRO (IT) 2020-12-30 EP claimed
EP-3662996-A2 MOLYBDENUM AND TUNGSTEN COMPLEXES AS OLEFIN METATHESIS CATALYSTS AND REACTIONS USING THE CATALYSTS Verbio Vereinigte BioEnergie AG (DE) 2020-06-10 EP claimed
US-20190300509-A1 MODULATORS OF SOCE, COMPOSITIONS, AND USES THEREOF UNIVERSITA DEGLI STUDI DEL PIEMONTE ORIENTALE "AMEDEO AVOGADRO" (IT) 2019-10-03 US claimed
US-10343153-B2 Metathesis catalysts and reactions using the catalysts XIMO AG (CH) 2019-07-09 US claimed
EP-3468964-A1 MODULATORS OF SOCE, COMPOSITIONS, AND USES THEREOF Università degli Studi del Piemonte Orientale "Amedeo Avogadro" (IT) 2019-04-17 EP claimed
EP-3377465-A2 PRODUCTION OF FATTY OLEFIN DERIVATIVES VIA OLEFIN METATHESIS Provivi, Inc. (US) 2018-09-26 EP claimed
WO-2017212414-A1 MODULATORS OF SOCE, COMPOSITIONS, AND USES THEREOF UNIVERSITÀ DEGLI STUDI DEL PIEMONTE ORIENTALE "AMEDEO AVOGADRO" (IT) 2017-12-14 WO claimed
WO-1998032812-A1 COMPOSITIONS INCLUDING A HYDROFLUOROPROPANE E.I. DU PONT DE NEMOURS AND COMPANY (US) 1998-07-30 WO claimed
EP-0842972-A1 Foams made with polyester polyols and hydrofluorocarbons as blowing agents THE CELOTEX CORPORATION (US) 1998-05-20 EP claimed
US-5496866-A OZONE FRIENDLY FOAMING AGENTS FOR POLYURETHANES BAYER AKTIENGESELLSCHAFT (DE) 1996-03-05 US claimed
US-5346645-A Desiccant composition and a method of desiccating articles DAIKIN INDUSTRIES, LTD. (JP) 1994-09-13 US claimed
US-5130345-A Forming a polyurethane or polyisocyanurate and foaming with a fluorine containing alkanes ALLIED-SIGNAL INC. (US) 1992-07-14 US claimed
WO-1992000345-A1 METHOD OF PREPARING FOAM USING A PARTIALLY FLUORINATED ALKANE ALLIED-SIGNAL INC. (US) 1992-01-09 WO claimed
EP-0218138-B1 NEW CATALYSTS PROCESS FOR THEIR PRODUCTION AND THEIR USE FOR EFFECTING METATHESIS OF OLEFINS MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 1989-01-11 EP claimed
US-4727215-A Catalyst composition for effecting metathesis of olefins MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 1988-02-23 US claimed
US-4681956-A Catalyst composition for effecting metathesis of olefins MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 1987-07-21 US claimed
EP-0218138-A1 New catalysts process for their production and their use for effecting metathesis of olefins MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 1987-04-15 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10343153-B2 Metathesis catalysts and reactions using the catalysts MSMO1, SQLE, MOGAT2 ALDH1A1 994/4885HSD17B10 479/4885
US-20190300509-A1 MODULATORS OF SOCE, COMPOSITIONS, AND USES THEREOF STIM1, ORAI1, SARAF ALDH1A1 1839/4885HSD17B10 4140/4885
US-11779911-B2 Production of fatty olefin derivatives via olefin metathesis SREBF1, F2, SREBF2 ALDH1A1 1913/4885HSD17B10 99/4885
US-20220032280-A1 PRODUCTION OF FATTY OLEFIN DERIVATIVES VIA OLEFIN METATHESIS SREBF1, F2, SREBF2 ALDH1A1 1913/4885HSD17B10 99/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.