SCHEMBL7780704

SCHEMBL7780704

CCC[Si](C)(C)OC(=O)C=CC(=O)O

nearest known ligand 0.50

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 11/20 0.50
ATM Q13315 1/20 0.35
TSHR P16473 2/20 0.35
TP53 P04637 1/20 0.35
EGLN1 Q9GZT9 1/20 0.35
EGLN3 Q9H6Z9 1/20 0.35
ALDH1A1 P00352 2/20 0.33
KDM4E B2RXH2 1/20 0.33
MAPT P10636 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
KEAP1 Q14145 1/20 0.30
NFE2L2 Q16236 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28365520 0.92 ATM (0.40) HCAR2ATMMAPTKEAP1NFE2L2
SCHEMBL28575319 0.89 HCAR2 (0.53) HCAR2ATMTDP1
SCHEMBL7778232 0.84 HCAR2 (0.52) HCAR2ATMTSHRTP53EGLN1
SCHEMBL10494071 0.80 HCAR2 (0.40) HCAR2TSHRTP53EGLN1EGLN3
SCHEMBL28365427 0.80 ATM (0.47) HCAR2ATMTSHRALDH1A1MAPT
SCHEMBL28365521 0.80 ATM (0.47) HCAR2ATMTSHRALDH1A1MAPT
SCHEMBL29274042 0.78 HCAR2 (0.42) HCAR2ALDH1A1
SCHEMBL7780710 0.77 HCAR2 (0.48) HCAR2TSHRTP53EGLN1EGLN3
SCHEMBL7780628 0.76 HCAR2 (0.42) HCAR2TSHRTP53EGLN1EGLN3
SCHEMBL1953080 0.74 FFAR3 (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0790289-B1 Polymeric material for liquid crystal/polymer composite film, record display medium, and use thereof DAINIPPON PRINTING CO LTD (JP) 2001-09-05 EP disclosed
US-5851422-A Polymeric material for liquid crystal/polymer composite film, record display medium, and use thereof DAI NIPPON PRINTING CO., LTD. (JP) 1998-12-22 US disclosed
EP-0790289-A1 Polymeric material for liquid crystal/polymer composite film, liquid crystal/polymer composite film, record display medium, and use thereof DAI NIPPON PRINTING CO., LTD. (JP) 1997-08-20 EP disclosed