SCHEMBL7778232

SCHEMBL7778232

CC[Si](C)(C)OC(=O)C=CC(=O)O

nearest known ligand 0.52

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 11/20 0.52
TSHR P16473 2/20 0.38
TP53 P04637 1/20 0.38
EGLN1 Q9GZT9 1/20 0.38
EGLN3 Q9H6Z9 1/20 0.38
ALDH1A1 P00352 2/20 0.34
KDM4E B2RXH2 1/20 0.34
MAPT P10636 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
ATM Q13315 1/20 0.33
KEAP1 Q14145 1/20 0.32
NFE2L2 Q16236 1/20 0.32
ALOX15 P16050 1/20 0.32
RECQL P46063 1/20 0.32
HSD17B10 Q99714 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7780704 0.84 HCAR2 (0.50) HCAR2TSHRTP53EGLN1EGLN3
SCHEMBL2144391 0.83 HCAR2 (0.54) HCAR2TSHRALDH1A1KDM4EMAPT
SCHEMBL2144396 0.83 HCAR2 (0.54) HCAR2TSHRALDH1A1KDM4EMAPT
SCHEMBL28575319 0.81 HCAR2 (0.53) HCAR2TDP1ATM
SCHEMBL7780710 0.80 HCAR2 (0.48) HCAR2TSHRTP53EGLN1EGLN3
SCHEMBL7780628 0.79 HCAR2 (0.42) HCAR2TSHRTP53EGLN1EGLN3
SCHEMBL9719311 0.78 HCAR2 (0.54) HCAR2TSHRTP53EGLN1EGLN3
SCHEMBL9719312 0.78 HCAR2 (0.54) HCAR2TSHRTP53EGLN1EGLN3
SCHEMBL28987278 0.78 HCAR2 (0.54) HCAR2TSHRTP53EGLN1EGLN3
SCHEMBL29406881 0.78 HCAR2 (0.54) HCAR2TSHRTP53EGLN1EGLN3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0790289-B1 Polymeric material for liquid crystal/polymer composite film, record display medium, and use thereof DAINIPPON PRINTING CO LTD (JP) 2001-09-05 EP disclosed
US-5851422-A Polymeric material for liquid crystal/polymer composite film, record display medium, and use thereof DAI NIPPON PRINTING CO., LTD. (JP) 1998-12-22 US disclosed
EP-0790289-A1 Polymeric material for liquid crystal/polymer composite film, liquid crystal/polymer composite film, record display medium, and use thereof DAI NIPPON PRINTING CO., LTD. (JP) 1997-08-20 EP disclosed