Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPKAPK2 | P49137 | 4/20 | 0.38 |
| ▸ | THRA | P10827 | 2/20 | 0.37 |
| ▸ | THRB | P10828 | 2/20 | 0.37 |
| ▸ | ACP3 | P15309 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | GSK3B | P49841 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | GFER | P55789 | 1/20 | 0.35 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CRHBP | P24387 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7785088 | 1.00 | ALDH1A1 (0.41) | ALDH1A1GAALMNAKMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL7803627 | 0.99 | ALDH1A1 (0.41) | ALDH1A1GAALMNAKMT2AMEN1 | |
| SCHEMBL7789345 | 0.94 | ALDH1A1 (0.46) | ALDH1A1GAALMNAKMT2AMEN1 | |
| SCHEMBL7785296 | 0.94 | ALDH1A1 (0.46) | ALDH1A1GAALMNAKMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL7785704 | 0.93 | ALDH1A1 (0.45) | ALDH1A1GAALMNAKMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL7785142 | 0.92 | KMT2A (0.44) | ALDH1A1GAALMNAKMT2AMEN1 | |
| SCHEMBL7805555 | 0.91 | MAPKAPK2 (0.38) | KMT2AMEN1POLBMAPKAPK2THRA | |
| SCHEMBL7785267 | 0.91 | MAPKAPK2 (0.38) | KMT2AMEN1POLBMAPKAPK2THRA | |
| Hydrochloric Acid SCHEMBL7787875 | 0.91 | MEN1 (0.45) | ALDH1A1GAALMNAKMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL7801450 | 0.91 | KMT2A (0.40) | ALDH1A1GAALMNAKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6329405-B1 | AS ILEAL BILE ACID TRANSPORTER INHIBITOR, FOR THERAPY OF HYPERLIPEMIA | SANKYO COMPANY, LIMITED (JP) | 2001-12-11 | — | — | US | claimed |
| EP-1070703-A1 | Cyclobutene derivatives | Sankyo Company Limited (JP) | 2001-01-24 | — | — | EP | disclosed |