Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 4/20 | 0.47 |
| ▸ | SRC | P12931 | 2/20 | 0.46 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA4 | P22748 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11154634 | 0.80 | HTT (0.64) | MAPTHTTSRCTGFBR1CYP3A4 | |
| SCHEMBL1753958 | 0.79 | HTT (0.52) | MAPTHTTSRCTGFBR1MAPK1 | |
| SCHEMBL13979264 | 0.79 | HTT (0.57) | MAPTHTTSRCTGFBR1MAPK1 | |
| SCHEMBL9097639 | 0.77 | NQO1 (0.58) | MAPTCYP3A4TSHRLMNAALDH1A1 | |
| SCHEMBL28930588 | 0.76 | HTT (0.58) | MAPTGAAHTTSRCTGFBR1 | |
| SCHEMBL7048626 | 0.76 | HTT (0.63) | MAPTGAAHTTMAPK1CYP3A4 | |
| SCHEMBL21953482 | 0.75 | PDE4A (0.47) | MAPTGAAHTTMAPK1CYP3A4 | |
| SCHEMBL1210111 | 0.75 | SRC (0.58) | MAPTHTTSRCTGFBR1CYP3A4 | |
| SCHEMBL30482833 | 0.75 | SRC (0.58) | MAPTHTTSRCTGFBR1CYP3A4 | |
| SCHEMBL1539328 | 0.74 | ALDH1A1 (0.49) | MAPTHTTSRCTGFBR1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1134216-A1 | ANTI-DRUG RESISTANT STRAIN AGENTS AND ANTICHLAMYDIA AGENTS | Japan Science and Technology Corporation (JP) | 2001-09-19 | — | — | EP | disclosed |