Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | SLC22A1 | O15245 | 2/20 | 0.36 |
| ▸ | NAAA | Q02083 | 2/20 | 0.32 |
| ▸ | DNM1 | Q05193 | 3/20 | 0.31 |
| ▸ | EPHX1 | P07099 | 5/20 | 0.31 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6061498 | 0.98 | CYP1A2 (0.44) | CYP1A2SLC22A1NAAADNM1EPHX1 | |
| Water SCHEMBL8942491 | 0.95 | CYP1A2 (0.43) | CYP1A2SLC22A1NAAADNM1EPHX1 | |
| Fluoride Ion SCHEMBL7550563 | 0.95 | CYP1A2 (0.43) | CYP1A2SLC22A1NAAADNM1EPHX1 | |
| Bromide SCHEMBL7781769 | 0.95 | CYP1A2 (0.43) | CYP1A2SLC22A1NAAADNM1EPHX1 | |
| SCHEMBL7548892 | 0.95 | CYP1A2 (0.41) | CYP1A2SLC22A1NAAADNM1SLC22A2 | |
| Fluoride Ion SCHEMBL7553479 | 0.93 | CYP1A2 (0.39) | CYP1A2SLC22A1DNM1SLC22A2 | |
| Water SCHEMBL7546065 | 0.93 | CYP1A2 (0.39) | CYP1A2SLC22A1DNM1SLC22A2 | |
| SCHEMBL7549210 | 0.93 | CYP1A2 (0.39) | CYP1A2SLC22A1DNM1SLC22A2 | |
| SCHEMBL7549208 | 0.93 | CYP1A2 (0.39) | CYP1A2SLC22A1DNM1SLC22A2 | |
| SCHEMBL14560949 | 0.89 | SLC22A1 (0.44) | CYP1A2SLC22A1DNM1SLC22A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0634407-B1 | Process for production of tris(tribromophenoxy)-s-triazine | DAI ICHI KOGYO SEIYAKU CO LTD (JP) | 2001-10-10 | — | — | EP | disclosed |
| US-6075142-A | CATALYTICALLY REACTING CYANURIC CHLORIDE AND AQUEOUS TRIBROMOPHENOLATE SOLUTION CONTAINING A REDUCING AGENT AND A PHASE TRANSFER CATALYST TO FORM TRIS/TRIBROMOPHENOXY/-S-TRAIZINE | DAI-ICHI KOGYO SEIYAKU CO., LTD. (JP) | 2000-06-13 | — | — | US | disclosed |
| EP-0735084-B1 | Flame retardant thermoplastic styrenic resin composition | DAI ICHI KOGYO SEIYAKU CO LTD (JP) | 2000-01-12 | — | — | EP | disclosed |
| EP-0633253-B1 | Process for production of tris(tribromophenoxy)-s-triazine | DAI ICHI KOGYO SEIYAKU CO LTD (JP) | 1999-09-01 | — | — | EP | disclosed |
| US-5907040-A | REACTION OF CYANURIC CHLORIDE WITH BROMOPHENOL AND TERT-AMINECATALYSTS | DAI-ICHI KOGYO SEIYAKU CO., LTD. (JP) | 1999-05-25 | — | — | US | disclosed |
| US-5696302-A | INTERMEDIATES FOR PRODUCING TRIS(TRIBROMOPHENOXY)-S-TRIAZINE | DAI-ICHI KOGYO SEIYAKU CO., LTD. (JP) | 1997-12-09 | — | — | US | disclosed |
| EP-0735084-A1 | Flame retardant thermoplastic styrenic resin composition | DAI-ICHI KOGYO SEIYAKU CO., LTD. (JP) | 1996-10-02 | — | — | EP | disclosed |
| US-5498714-A | FROM CYANURIC CHLORIDE AND TRIBROMOPHENOLATE, PHASE TRANSFER AGENT, REDUCING AGENT TO PREVENT POLYMERIZATION | DAI-ICHI KOGYO SEIYAKU CO., LTD. (JP) | 1996-03-12 | — | — | US | disclosed |
| EP-0634407-A1 | Process for production of tris(tribromophenoxy)-s-triazine | DAI-ICHI KOGYO SEIYAKU CO., LTD. (JP) | 1995-01-18 | — | — | EP | disclosed |
| EP-0633253-A1 | Process for production of tris(tribromophenoxy)-s-triazine | DAI-ICHI KOGYO SEIYAKU CO., LTD. (JP) | 1995-01-11 | — | — | EP | disclosed |