Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 1/20 | 0.58 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.37 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.37 |
| ▸ | NQO2 | P16083 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | SLC2A1 | P11166 | 2/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | HRH1 | P35367 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8418541 | 0.99 | ACACB (0.57) | ACACBMTNR1AMTNR1BNQO2SLC6A4 | |
| SCHEMBL5497655 | 0.88 | ACACB (0.58) | ACACBMTNR1AMTNR1BNQO2SIGMAR1 | |
| SCHEMBL7775681 | 0.87 | ACACB (0.60) | ACACBMTNR1AMTNR1BNQO2SLC2A1 | |
| SCHEMBL7780014 | 0.86 | ACACB (0.59) | ACACBMTNR1AMTNR1BNQO2SLC2A1 | |
| SCHEMBL4382039 | 0.85 | ACACB (0.67) | ACACBMTNR1AMTNR1BNQO2 | |
| SCHEMBL9236434 | 0.85 | ACACB (0.78) | ACACBMTNR1AMTNR1BNQO2 | |
| SCHEMBL7779969 | 0.85 | ACACB (0.78) | ACACBMTNR1AMTNR1BNQO2 | |
| SCHEMBL4382041 | 0.85 | ACACB (0.67) | ACACBMTNR1AMTNR1BNQO2 | |
| SCHEMBL4950105 | 0.85 | ACACB (0.67) | ACACBMTNR1AMTNR1BNQO2 | |
| SCHEMBL9239113 | 0.85 | ACACB (0.78) | ACACBMTNR1AMTNR1BNQO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0869952-B1 | 5-NAPHTHALEN-1-YL-1,3-DIOXANE DERIVATIVES, PREPARATION AND THERAPEUTICAL USE THEREOF | SANOFI SYNTHELABO (FR) | 2001-09-19 | — | — | EP | disclosed |
| EP-0869952-A1 | 5-NAPHTHALEN-1-YL-1,3-DIOXANE DERIVATIVES, PREPARATION AND THERAPEUTICAL USE THEREOF | SYNTHELABO (FR) | 1998-10-14 | — | — | EP | disclosed |
| WO-1997020836-A1 | 5-NAPHTHALEN-1-YL-1,3-DIOXANE DERIVATIVES, PREPARATION AND THERAPEUTICAL USE THEREOF | SYNTHELABO (FR) | 1997-06-12 | — | — | WO | disclosed |