Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 9/20 | 0.78 |
| ▸ | MTNR1A | P48039 | 10/20 | 0.53 |
| ▸ | MTNR1B | P49286 | 7/20 | 0.53 |
| ▸ | ACACA | Q13085 | 4/20 | 0.50 |
| ▸ | HTR2C | P28335 | 1/20 | 0.46 |
| ▸ | HTR2B | P41595 | 1/20 | 0.46 |
| ▸ | NQO2 | P16083 | 4/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7779969 | 1.00 | ACACB (0.78) | ACACBMTNR1AMTNR1BACACAHTR2C | |
| SCHEMBL9236434 | 1.00 | ACACB (0.78) | ACACBMTNR1AMTNR1BACACAHTR2C | |
| SCHEMBL4382041 | 0.92 | ACACB (0.67) | ACACBMTNR1AMTNR1BACACAHTR2C | |
| SCHEMBL4382039 | 0.92 | ACACB (0.67) | ACACBMTNR1AMTNR1BACACAHTR2C | |
| SCHEMBL4950105 | 0.92 | ACACB (0.67) | ACACBMTNR1AMTNR1BACACAHTR2C | |
| SCHEMBL8120495 | 0.90 | ACACB (0.76) | ACACBMTNR1AMTNR1BACACA | |
| SCHEMBL6469709 | 0.90 | ACACB (0.65) | ACACBMTNR1AMTNR1BACACAHTR2C | |
| SCHEMBL8109293 | 0.88 | ACACB (0.75) | ACACBMTNR1AMTNR1BACACA | |
| SCHEMBL8109688 | 0.88 | ACACB (1.00) | ACACBMTNR1AMTNR1BACACANQO2 | |
| SCHEMBL9235486 | 0.88 | ACACB (0.75) | ACACBMTNR1AMTNR1BACACA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0686394-A1 | Use of N-[[5-(naphthales-1-yl)-1,3-dioxan-2-yl]alkyl]acetamide derivatives for the preparation of medicaments for use in the treatment of neurodegenerative disorders | SYNTHELABO (FR) | 1995-12-13 | — | — | EP | claimed |
| JP-7330598-A | — | — | None | — | — | JP | disclosed |
| JP-H07330598-A | PHARMACEUTICAL COMPOSITION FOR TREATING NEURODEGENERATIVE DISORDER | SYNTHELABO SA | 1995-12-19 | — | — | JP | disclosed |
| EP-0686394-A1 | Use of N-[[5-(naphthales-1-yl)-1,3-dioxan-2-yl]alkyl]acetamide derivatives for the preparation of medicaments for use in the treatment of neurodegenerative disorders | SYNTHELABO (FR) | 1995-12-13 | — | — | EP | disclosed |